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Generation of a CD70-Specific Fusion Nanobody with IgG Recruiting Capacity for Tumor Killing

PURPOSE: Due to its competitive advantages such as small size, high stability, easy production, and good tissue penetration compared with monoclonal antibodies (mAb), nanobodies (Nbs) were considered the next generation of therapeutics. However, the absence of Fc fragments and Fc-triggered immune ef...

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Detalles Bibliográficos
Autores principales: Liu, Chang, Li, Jiangwei, Hu, Qianqian, Xu, Xinlan, Zhang, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10289098/
https://www.ncbi.nlm.nih.gov/pubmed/37361386
http://dx.doi.org/10.2147/IJN.S410281