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HSP90-Dependent Upregulation of EZH2 Promotes Hypoxia/Reoxygenation-Induced Pyroptosis by Inhibiting miR-22 in Endothelial Cells

OBJECTIVE: Endothelial cell pyroptosis induced by hypoxia/reoxygenation (H/R) plays a key role in the pathogenesis of myocardial infarction (MI). However, the underlying mechanism is not clearly elucidated. METHODS: Human umbilical vein endothelial cells (HUVECs) exposed to H/R acted as in vitro mod...

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Detalles Bibliográficos
Autores principales:	Deng, Paihe, Hu, Huimin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2023
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10289174/ https://www.ncbi.nlm.nih.gov/pubmed/37360624 http://dx.doi.org/10.2147/JIR.S403531

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