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Exploring regional disparities in lung cancer mortality in a Brazilian state: A cross-sectional ecological study
BACKGROUND: Lung cancer (LC) is one of the main causes of mortality in Brazil; geographic, cultural, socioeconomic and health access factors can affect the development of the disease. We explored the geospatial distribution of LC mortality, and associated factors, between 2015 and 2019, in Parana st...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10289318/ https://www.ncbi.nlm.nih.gov/pubmed/37352137 http://dx.doi.org/10.1371/journal.pone.0287371 |
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author | Dias Marques, Vlaudimir Massago, Miyoko da Silva, Mariana Teixeira Roskowski, Igor de Lima, Daniel Augusto Nunes dos Santos, Lander Louro, Estela Gonçalves, Simone Tomás Pedroso, Raissa Bocchi Obale, Armstrong Mbi Pelloso, Sandra Marisa Vissoci, João Ricardo Nickenig Staton, Catherine Ann Nihei, Oscar Kenji Carvalho, Maria Dalva de Barros Dutra, Amanda de Carvalho de Andrade, Luciano |
author_facet | Dias Marques, Vlaudimir Massago, Miyoko da Silva, Mariana Teixeira Roskowski, Igor de Lima, Daniel Augusto Nunes dos Santos, Lander Louro, Estela Gonçalves, Simone Tomás Pedroso, Raissa Bocchi Obale, Armstrong Mbi Pelloso, Sandra Marisa Vissoci, João Ricardo Nickenig Staton, Catherine Ann Nihei, Oscar Kenji Carvalho, Maria Dalva de Barros Dutra, Amanda de Carvalho de Andrade, Luciano |
author_sort | Dias Marques, Vlaudimir |
collection | PubMed |
description | BACKGROUND: Lung cancer (LC) is one of the main causes of mortality in Brazil; geographic, cultural, socioeconomic and health access factors can affect the development of the disease. We explored the geospatial distribution of LC mortality, and associated factors, between 2015 and 2019, in Parana state, Brazil. METHODS AND FINDINGS: We obtained mortality (from the Brazilian Health Informatics Department) and population rates (from the Brazilian Institute of Geography and Statistics [IBGE]) in people over 40 years old, accessibility of oncology centers by municipality, disease diagnosis rate (from Brazilian Ministry of Health), the tobacco production rate (IBGE) and Parana Municipal Performance Index (IPDM) (from Parana Institute for Economic and Social Development). Global Moran’s Index and Local Indicators of Spatial Association were performed to evaluate the spatial distribution of LC mortality in Parana state. Ordinary Least Squares Regression and Geographically Weighted Regression were used to verify spatial association between LC mortality and socioeconomic indicators and health service coverage. A strong spatial autocorrelation of LC mortality was observed, with the detection of a large cluster of high LC mortality in the South of Parana state. Spatial regression analysis showed that all independent variables analyzed were directly related to LC mortality by municipality in Paraná. CONCLUSIONS: There is a disparity in the LC mortality in Parana state, and inequality of socioeconomic and accessibility to health care services could be associated with it. Our findings may help health managers to intensify actions in regions with vulnerability in the detection and treatment of LC. |
format | Online Article Text |
id | pubmed-10289318 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-102893182023-06-24 Exploring regional disparities in lung cancer mortality in a Brazilian state: A cross-sectional ecological study Dias Marques, Vlaudimir Massago, Miyoko da Silva, Mariana Teixeira Roskowski, Igor de Lima, Daniel Augusto Nunes dos Santos, Lander Louro, Estela Gonçalves, Simone Tomás Pedroso, Raissa Bocchi Obale, Armstrong Mbi Pelloso, Sandra Marisa Vissoci, João Ricardo Nickenig Staton, Catherine Ann Nihei, Oscar Kenji Carvalho, Maria Dalva de Barros Dutra, Amanda de Carvalho de Andrade, Luciano PLoS One Research Article BACKGROUND: Lung cancer (LC) is one of the main causes of mortality in Brazil; geographic, cultural, socioeconomic and health access factors can affect the development of the disease. We explored the geospatial distribution of LC mortality, and associated factors, between 2015 and 2019, in Parana state, Brazil. METHODS AND FINDINGS: We obtained mortality (from the Brazilian Health Informatics Department) and population rates (from the Brazilian Institute of Geography and Statistics [IBGE]) in people over 40 years old, accessibility of oncology centers by municipality, disease diagnosis rate (from Brazilian Ministry of Health), the tobacco production rate (IBGE) and Parana Municipal Performance Index (IPDM) (from Parana Institute for Economic and Social Development). Global Moran’s Index and Local Indicators of Spatial Association were performed to evaluate the spatial distribution of LC mortality in Parana state. Ordinary Least Squares Regression and Geographically Weighted Regression were used to verify spatial association between LC mortality and socioeconomic indicators and health service coverage. A strong spatial autocorrelation of LC mortality was observed, with the detection of a large cluster of high LC mortality in the South of Parana state. Spatial regression analysis showed that all independent variables analyzed were directly related to LC mortality by municipality in Paraná. CONCLUSIONS: There is a disparity in the LC mortality in Parana state, and inequality of socioeconomic and accessibility to health care services could be associated with it. Our findings may help health managers to intensify actions in regions with vulnerability in the detection and treatment of LC. Public Library of Science 2023-06-23 /pmc/articles/PMC10289318/ /pubmed/37352137 http://dx.doi.org/10.1371/journal.pone.0287371 Text en © 2023 Dias Marques et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Dias Marques, Vlaudimir Massago, Miyoko da Silva, Mariana Teixeira Roskowski, Igor de Lima, Daniel Augusto Nunes dos Santos, Lander Louro, Estela Gonçalves, Simone Tomás Pedroso, Raissa Bocchi Obale, Armstrong Mbi Pelloso, Sandra Marisa Vissoci, João Ricardo Nickenig Staton, Catherine Ann Nihei, Oscar Kenji Carvalho, Maria Dalva de Barros Dutra, Amanda de Carvalho de Andrade, Luciano Exploring regional disparities in lung cancer mortality in a Brazilian state: A cross-sectional ecological study |
title | Exploring regional disparities in lung cancer mortality in a Brazilian state: A cross-sectional ecological study |
title_full | Exploring regional disparities in lung cancer mortality in a Brazilian state: A cross-sectional ecological study |
title_fullStr | Exploring regional disparities in lung cancer mortality in a Brazilian state: A cross-sectional ecological study |
title_full_unstemmed | Exploring regional disparities in lung cancer mortality in a Brazilian state: A cross-sectional ecological study |
title_short | Exploring regional disparities in lung cancer mortality in a Brazilian state: A cross-sectional ecological study |
title_sort | exploring regional disparities in lung cancer mortality in a brazilian state: a cross-sectional ecological study |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10289318/ https://www.ncbi.nlm.nih.gov/pubmed/37352137 http://dx.doi.org/10.1371/journal.pone.0287371 |
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