Release from persistent T cell receptor engagement and blockade of aryl hydrocarbon receptor activity enhance IL-6-dependent mouse follicular helper T-like cell differentiation in vitro

Follicular helper T (Tfh) cells are crucial for humoral immunity. Dysregulation of Tfh cell differentiation can cause infectious, allergic, and autoimmune diseases. To elucidate the molecular mechanisms underlying Tfh cell differentiation, we attempted to establish an in vitro mouse model of Tfh cel...

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Detalles Bibliográficos
Autores principales: Sakamoto, Rei, Takada, Ayumi, Yamakado, Shinnosuke, Tsuge, Haruki, Ito, Etsuro, Iwata, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10289413/
https://www.ncbi.nlm.nih.gov/pubmed/37352327
http://dx.doi.org/10.1371/journal.pone.0287746

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