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The analysis between clinicopathological aspect of early-onset vs. late-onset colorectal cancer and mortality rate: a cross-sectional study
Early-onset colorectal cancer (CRC) has different clinical and pathological characteristics compared with late-onset CRC. Mortality rate as a postoperative outcome is a patient’s postoperative outcome considered based on the state of life or death. The objective of this research is to analyse the co...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10289482/ https://www.ncbi.nlm.nih.gov/pubmed/37363503 http://dx.doi.org/10.1097/MS9.0000000000000757 |
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author | Lukman, Kiki Mulyawan, Andi Nugrahani, Annisa Dewi Rudiman, Reno Primastari, Etis |
author_facet | Lukman, Kiki Mulyawan, Andi Nugrahani, Annisa Dewi Rudiman, Reno Primastari, Etis |
author_sort | Lukman, Kiki |
collection | PubMed |
description | Early-onset colorectal cancer (CRC) has different clinical and pathological characteristics compared with late-onset CRC. Mortality rate as a postoperative outcome is a patient’s postoperative outcome considered based on the state of life or death. The objective of this research is to analyse the comparison between clinicopathological aspect of early-onset vs. late-onset CRC as well as their correlation with the mortality rate in Indonesia to support global data. MATERIAL AND METHODS: The authors performed a case-control study on 170 subjects with CRC from November 2021 to November 2022 in a Tertiary Hospital in Bandung. Data were extracted from electronic medical records CRC Registry. Bivariate and correlation analyses were used to analyse the difference between variables using IBM SPSS 24.0. P less than 0.05 was considered statistically significant. RESULTS: Anaemia and tumour location variables were significantly different in the early-onset group compared with the late-onset group (P<0.001). It was also found that anaemia (P<0.001), pathological features (P<0.001), and tumour location (P=0.013) had significantly low correlation with onset of CRC (r=0.325; r=0.397; r=0.342, respectively). CONCLUSION: There is no statistically significant correlation between the clinicopathological features of CRC in both onset and mortality rates in this study. |
format | Online Article Text |
id | pubmed-10289482 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Lippincott Williams & Wilkins |
record_format | MEDLINE/PubMed |
spelling | pubmed-102894822023-06-24 The analysis between clinicopathological aspect of early-onset vs. late-onset colorectal cancer and mortality rate: a cross-sectional study Lukman, Kiki Mulyawan, Andi Nugrahani, Annisa Dewi Rudiman, Reno Primastari, Etis Ann Med Surg (Lond) Original Research Early-onset colorectal cancer (CRC) has different clinical and pathological characteristics compared with late-onset CRC. Mortality rate as a postoperative outcome is a patient’s postoperative outcome considered based on the state of life or death. The objective of this research is to analyse the comparison between clinicopathological aspect of early-onset vs. late-onset CRC as well as their correlation with the mortality rate in Indonesia to support global data. MATERIAL AND METHODS: The authors performed a case-control study on 170 subjects with CRC from November 2021 to November 2022 in a Tertiary Hospital in Bandung. Data were extracted from electronic medical records CRC Registry. Bivariate and correlation analyses were used to analyse the difference between variables using IBM SPSS 24.0. P less than 0.05 was considered statistically significant. RESULTS: Anaemia and tumour location variables were significantly different in the early-onset group compared with the late-onset group (P<0.001). It was also found that anaemia (P<0.001), pathological features (P<0.001), and tumour location (P=0.013) had significantly low correlation with onset of CRC (r=0.325; r=0.397; r=0.342, respectively). CONCLUSION: There is no statistically significant correlation between the clinicopathological features of CRC in both onset and mortality rates in this study. Lippincott Williams & Wilkins 2023-05-03 /pmc/articles/PMC10289482/ /pubmed/37363503 http://dx.doi.org/10.1097/MS9.0000000000000757 Text en Copyright © 2023 The Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by-nd/4.0/This is an open access article distributed under the Creative Commons Attribution-NoDerivatives License 4.0 (https://creativecommons.org/licenses/by-nd/4.0/) , which allows for redistribution, commercial and non-commercial, as long as it is passed along unchanged and in whole, with credit to the author. http://creativecommons.org/licenses/by-nd/4.0/ (https://creativecommons.org/licenses/by-nd/4.0/) |
spellingShingle | Original Research Lukman, Kiki Mulyawan, Andi Nugrahani, Annisa Dewi Rudiman, Reno Primastari, Etis The analysis between clinicopathological aspect of early-onset vs. late-onset colorectal cancer and mortality rate: a cross-sectional study |
title | The analysis between clinicopathological aspect of early-onset vs. late-onset colorectal cancer and mortality rate: a cross-sectional study |
title_full | The analysis between clinicopathological aspect of early-onset vs. late-onset colorectal cancer and mortality rate: a cross-sectional study |
title_fullStr | The analysis between clinicopathological aspect of early-onset vs. late-onset colorectal cancer and mortality rate: a cross-sectional study |
title_full_unstemmed | The analysis between clinicopathological aspect of early-onset vs. late-onset colorectal cancer and mortality rate: a cross-sectional study |
title_short | The analysis between clinicopathological aspect of early-onset vs. late-onset colorectal cancer and mortality rate: a cross-sectional study |
title_sort | analysis between clinicopathological aspect of early-onset vs. late-onset colorectal cancer and mortality rate: a cross-sectional study |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10289482/ https://www.ncbi.nlm.nih.gov/pubmed/37363503 http://dx.doi.org/10.1097/MS9.0000000000000757 |
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