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Cushing syndrome caused by an ectopic ACTH-producing pituitary adenoma of the clivus region: A rare case report and literature review
Ectopic ACTH-producing pituitary adenoma (EAPA) of the clivus region is extraordinarily infrequent condition and merely a few reports have been reported to date. PATIENT CONCERNS: The patient was a 53-year-old woman who presented with Cushing-like appearances and a soft tissue mass in the clivus reg...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10289495/ https://www.ncbi.nlm.nih.gov/pubmed/37352051 http://dx.doi.org/10.1097/MD.0000000000034137 |
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author | He, Yutao Tang, Ziyi Tang, Na Lu, Yu Niu, Fangfang Ye, Jiao Zhang, Zheng Fang, Chenghong Yao, Lei |
author_facet | He, Yutao Tang, Ziyi Tang, Na Lu, Yu Niu, Fangfang Ye, Jiao Zhang, Zheng Fang, Chenghong Yao, Lei |
author_sort | He, Yutao |
collection | PubMed |
description | Ectopic ACTH-producing pituitary adenoma (EAPA) of the clivus region is extraordinarily infrequent condition and merely a few reports have been reported to date. PATIENT CONCERNS: The patient was a 53-year-old woman who presented with Cushing-like appearances and a soft tissue mass in the clivus region. DIAGNOSES: The final diagnosis of clivus region EAPA was established by clinical, radiological and histopathological findings. INTERVENTIONS: The patient underwent gross total clivus tumor resection via transsphenoidal endoscopy. OUTCOMES: Half a year after surgery, the patient Cushing-like clinical manifestations improved significantly, and urinary free cortisol and serum adrenocorticotropin (ACTH) returned to normal. LESSONS: Given the extreme scarcity of these tumors and their unique clinical presentations, it may be possible to misdiagnose and delayed treatment. Accordingly, it is especially crucial to summarize such lesions through our present case and review the literature for their precise diagnosis and the selection of optimal treatment strategies. |
format | Online Article Text |
id | pubmed-10289495 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Lippincott Williams & Wilkins |
record_format | MEDLINE/PubMed |
spelling | pubmed-102894952023-06-24 Cushing syndrome caused by an ectopic ACTH-producing pituitary adenoma of the clivus region: A rare case report and literature review He, Yutao Tang, Ziyi Tang, Na Lu, Yu Niu, Fangfang Ye, Jiao Zhang, Zheng Fang, Chenghong Yao, Lei Medicine (Baltimore) 4100 Ectopic ACTH-producing pituitary adenoma (EAPA) of the clivus region is extraordinarily infrequent condition and merely a few reports have been reported to date. PATIENT CONCERNS: The patient was a 53-year-old woman who presented with Cushing-like appearances and a soft tissue mass in the clivus region. DIAGNOSES: The final diagnosis of clivus region EAPA was established by clinical, radiological and histopathological findings. INTERVENTIONS: The patient underwent gross total clivus tumor resection via transsphenoidal endoscopy. OUTCOMES: Half a year after surgery, the patient Cushing-like clinical manifestations improved significantly, and urinary free cortisol and serum adrenocorticotropin (ACTH) returned to normal. LESSONS: Given the extreme scarcity of these tumors and their unique clinical presentations, it may be possible to misdiagnose and delayed treatment. Accordingly, it is especially crucial to summarize such lesions through our present case and review the literature for their precise diagnosis and the selection of optimal treatment strategies. Lippincott Williams & Wilkins 2023-06-23 /pmc/articles/PMC10289495/ /pubmed/37352051 http://dx.doi.org/10.1097/MD.0000000000034137 Text en Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY) (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | 4100 He, Yutao Tang, Ziyi Tang, Na Lu, Yu Niu, Fangfang Ye, Jiao Zhang, Zheng Fang, Chenghong Yao, Lei Cushing syndrome caused by an ectopic ACTH-producing pituitary adenoma of the clivus region: A rare case report and literature review |
title | Cushing syndrome caused by an ectopic ACTH-producing pituitary adenoma of the clivus region: A rare case report and literature review |
title_full | Cushing syndrome caused by an ectopic ACTH-producing pituitary adenoma of the clivus region: A rare case report and literature review |
title_fullStr | Cushing syndrome caused by an ectopic ACTH-producing pituitary adenoma of the clivus region: A rare case report and literature review |
title_full_unstemmed | Cushing syndrome caused by an ectopic ACTH-producing pituitary adenoma of the clivus region: A rare case report and literature review |
title_short | Cushing syndrome caused by an ectopic ACTH-producing pituitary adenoma of the clivus region: A rare case report and literature review |
title_sort | cushing syndrome caused by an ectopic acth-producing pituitary adenoma of the clivus region: a rare case report and literature review |
topic | 4100 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10289495/ https://www.ncbi.nlm.nih.gov/pubmed/37352051 http://dx.doi.org/10.1097/MD.0000000000034137 |
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