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Systemic sclerosis with interstitial lung disease and myocardial infarction: a case report

Systemic sclerosis (SSc) is a rare autoimmune connective tissue disorder that causes fibrosis due to an accelerated inflammatory response. One of the most frequent co-morbidities with SSc is interstitial lung disease (ILD), which is also one of the biggest killers among SSc patients. CASE PRESENTATI...

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Autores principales: Adhikari, Sagar, Poudel, Priyanka, Pathak, Sujan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10289606/
https://www.ncbi.nlm.nih.gov/pubmed/37363557
http://dx.doi.org/10.1097/MS9.0000000000000740
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author Adhikari, Sagar
Poudel, Priyanka
Pathak, Sujan
author_facet Adhikari, Sagar
Poudel, Priyanka
Pathak, Sujan
author_sort Adhikari, Sagar
collection PubMed
description Systemic sclerosis (SSc) is a rare autoimmune connective tissue disorder that causes fibrosis due to an accelerated inflammatory response. One of the most frequent co-morbidities with SSc is interstitial lung disease (ILD), which is also one of the biggest killers among SSc patients. CASE PRESENTATION: The authors present a rare case of diffuse SSc with ILD and myocardial infarction having a history of Raynaud phenomenon, skin thickening, and shortness of breath. Antinuclear antibody and antitopoisomerase antibody tests were positive. The patient was managed medically and the condition of patient is improving. CLINICAL DISCUSSION: SSC can affect the skin as well as other organs, with the lungs being the most frequently involved and seriously impacted. SSc patients can have multiple organ involvement like the skin, lungs, heart, kidneys, and gastrointestinal tract. Because ILD is the leading cause of death among people with SSC, early diagnosis and high suspicion of lung involvement can reduce mortality. CONCLUSION: The mortality rate for SSC associated with ILD is extremely high. Even though ILD is common in SSc, it might be difficult to identify and detect early for which a high-resolution CT scan can be used. In SSc patients, heart involvement can coexist with ILD.
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spelling pubmed-102896062023-06-24 Systemic sclerosis with interstitial lung disease and myocardial infarction: a case report Adhikari, Sagar Poudel, Priyanka Pathak, Sujan Ann Med Surg (Lond) Case Reports Systemic sclerosis (SSc) is a rare autoimmune connective tissue disorder that causes fibrosis due to an accelerated inflammatory response. One of the most frequent co-morbidities with SSc is interstitial lung disease (ILD), which is also one of the biggest killers among SSc patients. CASE PRESENTATION: The authors present a rare case of diffuse SSc with ILD and myocardial infarction having a history of Raynaud phenomenon, skin thickening, and shortness of breath. Antinuclear antibody and antitopoisomerase antibody tests were positive. The patient was managed medically and the condition of patient is improving. CLINICAL DISCUSSION: SSC can affect the skin as well as other organs, with the lungs being the most frequently involved and seriously impacted. SSc patients can have multiple organ involvement like the skin, lungs, heart, kidneys, and gastrointestinal tract. Because ILD is the leading cause of death among people with SSC, early diagnosis and high suspicion of lung involvement can reduce mortality. CONCLUSION: The mortality rate for SSC associated with ILD is extremely high. Even though ILD is common in SSc, it might be difficult to identify and detect early for which a high-resolution CT scan can be used. In SSc patients, heart involvement can coexist with ILD. Lippincott Williams & Wilkins 2023-05-04 /pmc/articles/PMC10289606/ /pubmed/37363557 http://dx.doi.org/10.1097/MS9.0000000000000740 Text en Copyright © 2023 The Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/)
spellingShingle Case Reports
Adhikari, Sagar
Poudel, Priyanka
Pathak, Sujan
Systemic sclerosis with interstitial lung disease and myocardial infarction: a case report
title Systemic sclerosis with interstitial lung disease and myocardial infarction: a case report
title_full Systemic sclerosis with interstitial lung disease and myocardial infarction: a case report
title_fullStr Systemic sclerosis with interstitial lung disease and myocardial infarction: a case report
title_full_unstemmed Systemic sclerosis with interstitial lung disease and myocardial infarction: a case report
title_short Systemic sclerosis with interstitial lung disease and myocardial infarction: a case report
title_sort systemic sclerosis with interstitial lung disease and myocardial infarction: a case report
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10289606/
https://www.ncbi.nlm.nih.gov/pubmed/37363557
http://dx.doi.org/10.1097/MS9.0000000000000740
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