Optogenetic-induced muscle loading leads to mechanical adaptation of the Achilles tendon enthesis in mice

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Skeletal shape depends on the transmission of contractile muscle forces from tendon to bone across the enthesis. Loss of muscle loading impairs enthesis development, yet little is known if and how the postnatal enthesis adapts to increased loading. Here, we studied adaptations in enthesis structure...

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Detalles Bibliográficos
Autores principales: Ganji, Elahe, Lamia, Syeda N., Stepanovich, Matthew, Whyte, Noelle, Goulet, Robert W., Abraham, Adam C., Killian, Megan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10289645/
https://www.ncbi.nlm.nih.gov/pubmed/37352350
http://dx.doi.org/10.1126/sciadv.adf4683
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