Quantitative measurement of the requirement of diverse protein degradation pathways in MHC class I peptide presentation

Peptides from degradation of intracellular proteins are continuously displayed by major histocompatibility complex (MHC) class I. To better understand origins of these peptides, we performed a comprehensive census of the class I peptide repertoire in the presence and absence of ubiquitin-proteasome...

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Detalles Bibliográficos
Autores principales: Mamrosh, Jennifer L., Sherman, David J., Cohen, Joseph R., Johnston, James A., Joubert, Marisa K., Li, Jing, Lipford, J. Russell, Lomenick, Brett, Moradian, Annie, Prabhu, Siddharth, Sweredoski, Michael J., Vander Lugt, Bryan, Verma, Rati, Deshaies, Raymond J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10289651/
https://www.ncbi.nlm.nih.gov/pubmed/37352349
http://dx.doi.org/10.1126/sciadv.ade7890

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