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An independent regulator of global release pathways in astrocytes generates a subtype of extracellular vesicles required for postsynaptic function
Extracellular vesicles (EVs) are heterogeneous in size, composition, and function. We show that the six-transmembrane protein glycerophosphodiester phosphodiesterase 3 (GDE3) regulates actin remodeling, a global EV biogenic pathway, to release an EV subtype with distinct functions. GDE3 is necessary...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Association for the Advancement of Science
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10289663/ https://www.ncbi.nlm.nih.gov/pubmed/37352348 http://dx.doi.org/10.1126/sciadv.adg2067 |