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Could initial CT chest manifestation in patients hospitalized with COVID 19 pneumonia predict outcome on short term basis
Chest computed tomography (CT) can be used to monitor the course of the disease or response to therapy. Therefore, our study was designed to identify chest CT manifestations that can predict the outcome of patients on short term follow-up. This was a retrospective study wherein we reviewed chest CT...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10289672/ https://www.ncbi.nlm.nih.gov/pubmed/37352045 http://dx.doi.org/10.1097/MD.0000000000034115 |
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author | Dola, Eman F. Nakhla, Osama Lamie Alkaphoury, Mona Gamalludin |
author_facet | Dola, Eman F. Nakhla, Osama Lamie Alkaphoury, Mona Gamalludin |
author_sort | Dola, Eman F. |
collection | PubMed |
description | Chest computed tomography (CT) can be used to monitor the course of the disease or response to therapy. Therefore, our study was designed to identify chest CT manifestations that can predict the outcome of patients on short term follow-up. This was a retrospective study wherein we reviewed chest CT scans of 112 real-time reverse transcription polymerase chain reaction positive patients admitted to our hospital. All 112 patients underwent follow-up chest CT at a time interval of 4 to 42 days. Our study included 83 male and 29 female who were positive for COVID 19 infection and admitted to the hospital with positive chest CT findings. All patients underwent follow-up chest CT, and the outcomes were categorized as resolution, regression, residual fibrosis, progression, or death. These proportions were 5.4%, 48.2%, 24.1%, 14.3%, and 8%, respectively. The only significant factor in determining the complete resolution of chest CT was oligo-segmental affection (P = .0001). The main CT feature that significantly affected the regression of chest CT manifestations was diffuse nodular shadows (P = .039). The CT features noted in patients with residual fibrosis were interstitial thickening, with a P value of .017. The mono-segmental process significantly affected progression (P = .044). The significant factors for fatality were diffuse crazy paving, pleural effusion, and extra-thoracic complications (P = .033, .029, and .007, respectively). The prognostic value of the first admission CT can help assess disease outcomes in the earliest phases of onset. This can improve resource distribution. |
format | Online Article Text |
id | pubmed-10289672 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Lippincott Williams & Wilkins |
record_format | MEDLINE/PubMed |
spelling | pubmed-102896722023-06-24 Could initial CT chest manifestation in patients hospitalized with COVID 19 pneumonia predict outcome on short term basis Dola, Eman F. Nakhla, Osama Lamie Alkaphoury, Mona Gamalludin Medicine (Baltimore) 6800 Chest computed tomography (CT) can be used to monitor the course of the disease or response to therapy. Therefore, our study was designed to identify chest CT manifestations that can predict the outcome of patients on short term follow-up. This was a retrospective study wherein we reviewed chest CT scans of 112 real-time reverse transcription polymerase chain reaction positive patients admitted to our hospital. All 112 patients underwent follow-up chest CT at a time interval of 4 to 42 days. Our study included 83 male and 29 female who were positive for COVID 19 infection and admitted to the hospital with positive chest CT findings. All patients underwent follow-up chest CT, and the outcomes were categorized as resolution, regression, residual fibrosis, progression, or death. These proportions were 5.4%, 48.2%, 24.1%, 14.3%, and 8%, respectively. The only significant factor in determining the complete resolution of chest CT was oligo-segmental affection (P = .0001). The main CT feature that significantly affected the regression of chest CT manifestations was diffuse nodular shadows (P = .039). The CT features noted in patients with residual fibrosis were interstitial thickening, with a P value of .017. The mono-segmental process significantly affected progression (P = .044). The significant factors for fatality were diffuse crazy paving, pleural effusion, and extra-thoracic complications (P = .033, .029, and .007, respectively). The prognostic value of the first admission CT can help assess disease outcomes in the earliest phases of onset. This can improve resource distribution. Lippincott Williams & Wilkins 2023-06-23 /pmc/articles/PMC10289672/ /pubmed/37352045 http://dx.doi.org/10.1097/MD.0000000000034115 Text en Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY) (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | 6800 Dola, Eman F. Nakhla, Osama Lamie Alkaphoury, Mona Gamalludin Could initial CT chest manifestation in patients hospitalized with COVID 19 pneumonia predict outcome on short term basis |
title | Could initial CT chest manifestation in patients hospitalized with COVID 19 pneumonia predict outcome on short term basis |
title_full | Could initial CT chest manifestation in patients hospitalized with COVID 19 pneumonia predict outcome on short term basis |
title_fullStr | Could initial CT chest manifestation in patients hospitalized with COVID 19 pneumonia predict outcome on short term basis |
title_full_unstemmed | Could initial CT chest manifestation in patients hospitalized with COVID 19 pneumonia predict outcome on short term basis |
title_short | Could initial CT chest manifestation in patients hospitalized with COVID 19 pneumonia predict outcome on short term basis |
title_sort | could initial ct chest manifestation in patients hospitalized with covid 19 pneumonia predict outcome on short term basis |
topic | 6800 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10289672/ https://www.ncbi.nlm.nih.gov/pubmed/37352045 http://dx.doi.org/10.1097/MD.0000000000034115 |
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