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Could initial CT chest manifestation in patients hospitalized with COVID 19 pneumonia predict outcome on short term basis

Chest computed tomography (CT) can be used to monitor the course of the disease or response to therapy. Therefore, our study was designed to identify chest CT manifestations that can predict the outcome of patients on short term follow-up. This was a retrospective study wherein we reviewed chest CT...

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Autores principales: Dola, Eman F., Nakhla, Osama Lamie, Alkaphoury, Mona Gamalludin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10289672/
https://www.ncbi.nlm.nih.gov/pubmed/37352045
http://dx.doi.org/10.1097/MD.0000000000034115
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author Dola, Eman F.
Nakhla, Osama Lamie
Alkaphoury, Mona Gamalludin
author_facet Dola, Eman F.
Nakhla, Osama Lamie
Alkaphoury, Mona Gamalludin
author_sort Dola, Eman F.
collection PubMed
description Chest computed tomography (CT) can be used to monitor the course of the disease or response to therapy. Therefore, our study was designed to identify chest CT manifestations that can predict the outcome of patients on short term follow-up. This was a retrospective study wherein we reviewed chest CT scans of 112 real-time reverse transcription polymerase chain reaction positive patients admitted to our hospital. All 112 patients underwent follow-up chest CT at a time interval of 4 to 42 days. Our study included 83 male and 29 female who were positive for COVID 19 infection and admitted to the hospital with positive chest CT findings. All patients underwent follow-up chest CT, and the outcomes were categorized as resolution, regression, residual fibrosis, progression, or death. These proportions were 5.4%, 48.2%, 24.1%, 14.3%, and 8%, respectively. The only significant factor in determining the complete resolution of chest CT was oligo-segmental affection (P = .0001). The main CT feature that significantly affected the regression of chest CT manifestations was diffuse nodular shadows (P = .039). The CT features noted in patients with residual fibrosis were interstitial thickening, with a P value of .017. The mono-segmental process significantly affected progression (P = .044). The significant factors for fatality were diffuse crazy paving, pleural effusion, and extra-thoracic complications (P = .033, .029, and .007, respectively). The prognostic value of the first admission CT can help assess disease outcomes in the earliest phases of onset. This can improve resource distribution.
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spelling pubmed-102896722023-06-24 Could initial CT chest manifestation in patients hospitalized with COVID 19 pneumonia predict outcome on short term basis Dola, Eman F. Nakhla, Osama Lamie Alkaphoury, Mona Gamalludin Medicine (Baltimore) 6800 Chest computed tomography (CT) can be used to monitor the course of the disease or response to therapy. Therefore, our study was designed to identify chest CT manifestations that can predict the outcome of patients on short term follow-up. This was a retrospective study wherein we reviewed chest CT scans of 112 real-time reverse transcription polymerase chain reaction positive patients admitted to our hospital. All 112 patients underwent follow-up chest CT at a time interval of 4 to 42 days. Our study included 83 male and 29 female who were positive for COVID 19 infection and admitted to the hospital with positive chest CT findings. All patients underwent follow-up chest CT, and the outcomes were categorized as resolution, regression, residual fibrosis, progression, or death. These proportions were 5.4%, 48.2%, 24.1%, 14.3%, and 8%, respectively. The only significant factor in determining the complete resolution of chest CT was oligo-segmental affection (P = .0001). The main CT feature that significantly affected the regression of chest CT manifestations was diffuse nodular shadows (P = .039). The CT features noted in patients with residual fibrosis were interstitial thickening, with a P value of .017. The mono-segmental process significantly affected progression (P = .044). The significant factors for fatality were diffuse crazy paving, pleural effusion, and extra-thoracic complications (P = .033, .029, and .007, respectively). The prognostic value of the first admission CT can help assess disease outcomes in the earliest phases of onset. This can improve resource distribution. Lippincott Williams & Wilkins 2023-06-23 /pmc/articles/PMC10289672/ /pubmed/37352045 http://dx.doi.org/10.1097/MD.0000000000034115 Text en Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY) (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle 6800
Dola, Eman F.
Nakhla, Osama Lamie
Alkaphoury, Mona Gamalludin
Could initial CT chest manifestation in patients hospitalized with COVID 19 pneumonia predict outcome on short term basis
title Could initial CT chest manifestation in patients hospitalized with COVID 19 pneumonia predict outcome on short term basis
title_full Could initial CT chest manifestation in patients hospitalized with COVID 19 pneumonia predict outcome on short term basis
title_fullStr Could initial CT chest manifestation in patients hospitalized with COVID 19 pneumonia predict outcome on short term basis
title_full_unstemmed Could initial CT chest manifestation in patients hospitalized with COVID 19 pneumonia predict outcome on short term basis
title_short Could initial CT chest manifestation in patients hospitalized with COVID 19 pneumonia predict outcome on short term basis
title_sort could initial ct chest manifestation in patients hospitalized with covid 19 pneumonia predict outcome on short term basis
topic 6800
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10289672/
https://www.ncbi.nlm.nih.gov/pubmed/37352045
http://dx.doi.org/10.1097/MD.0000000000034115
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