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Genetic variation of the HIV-1 subtype C transmitted/founder viruses long terminal repeat elements and the impact on transcription activation potential and clinical disease outcomes

A genetic bottleneck is a hallmark of HIV-1 transmission such that only very few viral strains, termed transmitted/founder (T/F) variants establish infection in a newly infected host. Phenotypic characteristics of these variants may determine the subsequent course of disease. The HIV-1 5’ long termi...

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Detalles Bibliográficos
Autores principales:	Madlala, Paradise, Mkhize, Zakithi, Naicker, Shamara, Khathi, Samukelisiwe P., Maikoo, Shreyal, Gopee, Kasmira, Dong, Krista L., Ndung’u, Thumbi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10289673/ https://www.ncbi.nlm.nih.gov/pubmed/37307292 http://dx.doi.org/10.1371/journal.ppat.1011194

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