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Ventilator associated pneumonia in intensive care unit patients: a systematic review
Ventilator-associated pneumonia (VAP) is the most common ICU acquired pneumonia among patients who are invasively intubated for mechanical ventilation. Patients with VAP suffer an increased mortality risk, financial burden, and length of stay in the hospital. The authors aimed to review the literatu...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10289715/ https://www.ncbi.nlm.nih.gov/pubmed/37363470 http://dx.doi.org/10.1097/MS9.0000000000000836 |
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author | Mumtaz, Hassan Saqib, Muhammad Khan, Wajiha Ismail, Syed M. Sohail, Hassan Muneeb, Muhammad Sheikh, Shazia S. |
author_facet | Mumtaz, Hassan Saqib, Muhammad Khan, Wajiha Ismail, Syed M. Sohail, Hassan Muneeb, Muhammad Sheikh, Shazia S. |
author_sort | Mumtaz, Hassan |
collection | PubMed |
description | Ventilator-associated pneumonia (VAP) is the most common ICU acquired pneumonia among patients who are invasively intubated for mechanical ventilation. Patients with VAP suffer an increased mortality risk, financial burden, and length of stay in the hospital. The authors aimed to review the literature to describe the incidence, mortality, and microbiological evidence of VAP. We selected 13 peer-reviewed articles published from 1 January 2010 to 15 September 2022 from electronic databases for studies among adult or pediatric patients diagnosed with VAP expressed per thousand days admitted in the ICU. The VAP rates ranged from 7 to 43 per thousand days, varying among different countries of the world. A significant rate of mortality was observed in 13 studies ranging from 6.3 to 66.9%. Gram-negative organisms like Acinetobacter spp., Pseudomonas aeruginosa Gram-positive organisms like Staphylococcus aureus were frequently found. Our findings suggest an alarming situation of VAP among patients admitted to the intensive care units with increasing incidence and mortality. The review also found that VAP is more common in males and that there is a significant variation in the incidence and mortality rates of VAP among different countries. The findings of this review can inform the development of infection control and prevention strategies to reduce the burden of VAP. Thus, there is a crucial need for control and preventive measures like interventional studies and educational programs on staff training, hand-hygiene, and the appropriate use of ventilator bundle approach to curb this preventable threat that is increasing at an alarming rate. |
format | Online Article Text |
id | pubmed-10289715 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Lippincott Williams & Wilkins |
record_format | MEDLINE/PubMed |
spelling | pubmed-102897152023-06-24 Ventilator associated pneumonia in intensive care unit patients: a systematic review Mumtaz, Hassan Saqib, Muhammad Khan, Wajiha Ismail, Syed M. Sohail, Hassan Muneeb, Muhammad Sheikh, Shazia S. Ann Med Surg (Lond) Review Articles Ventilator-associated pneumonia (VAP) is the most common ICU acquired pneumonia among patients who are invasively intubated for mechanical ventilation. Patients with VAP suffer an increased mortality risk, financial burden, and length of stay in the hospital. The authors aimed to review the literature to describe the incidence, mortality, and microbiological evidence of VAP. We selected 13 peer-reviewed articles published from 1 January 2010 to 15 September 2022 from electronic databases for studies among adult or pediatric patients diagnosed with VAP expressed per thousand days admitted in the ICU. The VAP rates ranged from 7 to 43 per thousand days, varying among different countries of the world. A significant rate of mortality was observed in 13 studies ranging from 6.3 to 66.9%. Gram-negative organisms like Acinetobacter spp., Pseudomonas aeruginosa Gram-positive organisms like Staphylococcus aureus were frequently found. Our findings suggest an alarming situation of VAP among patients admitted to the intensive care units with increasing incidence and mortality. The review also found that VAP is more common in males and that there is a significant variation in the incidence and mortality rates of VAP among different countries. The findings of this review can inform the development of infection control and prevention strategies to reduce the burden of VAP. Thus, there is a crucial need for control and preventive measures like interventional studies and educational programs on staff training, hand-hygiene, and the appropriate use of ventilator bundle approach to curb this preventable threat that is increasing at an alarming rate. Lippincott Williams & Wilkins 2023-05-12 /pmc/articles/PMC10289715/ /pubmed/37363470 http://dx.doi.org/10.1097/MS9.0000000000000836 Text en Copyright © 2023 The Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (https://creativecommons.org/licenses/by-nc/4.0/) (CCBY-NC), where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) |
spellingShingle | Review Articles Mumtaz, Hassan Saqib, Muhammad Khan, Wajiha Ismail, Syed M. Sohail, Hassan Muneeb, Muhammad Sheikh, Shazia S. Ventilator associated pneumonia in intensive care unit patients: a systematic review |
title | Ventilator associated pneumonia in intensive care unit patients: a systematic review |
title_full | Ventilator associated pneumonia in intensive care unit patients: a systematic review |
title_fullStr | Ventilator associated pneumonia in intensive care unit patients: a systematic review |
title_full_unstemmed | Ventilator associated pneumonia in intensive care unit patients: a systematic review |
title_short | Ventilator associated pneumonia in intensive care unit patients: a systematic review |
title_sort | ventilator associated pneumonia in intensive care unit patients: a systematic review |
topic | Review Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10289715/ https://www.ncbi.nlm.nih.gov/pubmed/37363470 http://dx.doi.org/10.1097/MS9.0000000000000836 |
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