A DNA-PK phosphorylation site on MET regulates its signaling interface with the DNA damage response

The DNA damage response (DDR) is intertwined with signaling pathways downstream of oncogenic receptor tyrosine kinases (RTKs). To drive research into the application of targeted therapies as radiosensitizers, a better understanding of this molecular crosstalk is necessary. We present here the charac...

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Detalles Bibliográficos
Autores principales: Koch, Jonas P., Roth, Selina M., Quintin, Aurélie, Gavini, Jacopo, Orlando, Eleonora, Riedo, Rahel, Pozzato, Chiara, Hayrapetyan, Liana, Aebersold, Ruedi, Stroka, Deborah M., Aebersold, Daniel M., Medo, Matúš, Zimmer, Yitzhak, Medová, Michaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10289896/
https://www.ncbi.nlm.nih.gov/pubmed/37188738
http://dx.doi.org/10.1038/s41388-023-02714-6

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