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Human artificial chromosome carrying 3p21.3-p22.2 region suppresses hTERT transcription in oral cancer cells
Telomerase is a ribonucleoprotein ribonucleic enzyme that elongates telomere repeat sequences at the ends of chromosomes and contributes to cellular immortalization. The catalytic component of telomerase, human telomerase reverse transcriptase (hTERT), has been observed to be reactivated in immortal...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10289923/ https://www.ncbi.nlm.nih.gov/pubmed/37353691 http://dx.doi.org/10.1007/s10577-023-09726-8 |