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Human artificial chromosome carrying 3p21.3-p22.2 region suppresses hTERT transcription in oral cancer cells

Telomerase is a ribonucleoprotein ribonucleic enzyme that elongates telomere repeat sequences at the ends of chromosomes and contributes to cellular immortalization. The catalytic component of telomerase, human telomerase reverse transcriptase (hTERT), has been observed to be reactivated in immortal...

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Detalles Bibliográficos
Autores principales: Ohira, Takahito, Yoshimura, Kaho, Kugoh, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10289923/
https://www.ncbi.nlm.nih.gov/pubmed/37353691
http://dx.doi.org/10.1007/s10577-023-09726-8

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