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Operative Therapie von Nävi bei Kindern in einem dermatochirurgischen Zentrum: Histopathologie und Komplikationen

BACKGROUND: The indication for surgical management and histological diagnosis of melanocytic nevi in children is a major challenge in clinical routine. In consultations with children and parents, the exclusion of malignant findings, on the one hand, and the risk of complications, on the other hand,...

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Autores principales: Kofler, Katrin, Häfner, Hans-Martin, Forchhammer, Stephan, Kofler, Lukas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Medizin 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10290004/
https://www.ncbi.nlm.nih.gov/pubmed/37119200
http://dx.doi.org/10.1007/s00105-023-05147-0
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author Kofler, Katrin
Häfner, Hans-Martin
Forchhammer, Stephan
Kofler, Lukas
author_facet Kofler, Katrin
Häfner, Hans-Martin
Forchhammer, Stephan
Kofler, Lukas
author_sort Kofler, Katrin
collection PubMed
description BACKGROUND: The indication for surgical management and histological diagnosis of melanocytic nevi in children is a major challenge in clinical routine. In consultations with children and parents, the exclusion of malignant findings, on the one hand, and the risk of complications, on the other hand, are important. PATIENTS AND METHODOLOGY: Included were 946 children under the age of 10 years who underwent surgery with a suspected diagnosis of melanocytic nevus at the University Department of Dermatology, Tübingen, Germany, between 2008 and 2018. Dermatohistopathologic findings and postoperative complications were recorded. RESULTS: A clinical diagnosis of melanocytic nevus was histologically confirmed in 93.2% (882/946) of cases, whereby there were 41 Spitz nevi and 18 pigmented spindle cell tumors. Melanoma was diagnosed in 2 of the children (0.2%). In another 6.6%, non-melanocytic findings (e.g., nevus sebaceous, epidermal nevi) were diagnosed. The complication rate was low at 3%. The most common complication was the occurrence of postoperative wound infection in 1.7%. CONCLUSION: It is possible to take a biopsy or surgically remove congenital nevi of different sizes even in infants. Serial excision of congenital nevi is an important tool for this purpose. In the investigated cohort, the complication rate was low. Histological confirmation is essential in case of clinically suspicious or atypical findings.
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spelling pubmed-102900042023-06-25 Operative Therapie von Nävi bei Kindern in einem dermatochirurgischen Zentrum: Histopathologie und Komplikationen Kofler, Katrin Häfner, Hans-Martin Forchhammer, Stephan Kofler, Lukas Dermatologie (Heidelb) Originalien BACKGROUND: The indication for surgical management and histological diagnosis of melanocytic nevi in children is a major challenge in clinical routine. In consultations with children and parents, the exclusion of malignant findings, on the one hand, and the risk of complications, on the other hand, are important. PATIENTS AND METHODOLOGY: Included were 946 children under the age of 10 years who underwent surgery with a suspected diagnosis of melanocytic nevus at the University Department of Dermatology, Tübingen, Germany, between 2008 and 2018. Dermatohistopathologic findings and postoperative complications were recorded. RESULTS: A clinical diagnosis of melanocytic nevus was histologically confirmed in 93.2% (882/946) of cases, whereby there were 41 Spitz nevi and 18 pigmented spindle cell tumors. Melanoma was diagnosed in 2 of the children (0.2%). In another 6.6%, non-melanocytic findings (e.g., nevus sebaceous, epidermal nevi) were diagnosed. The complication rate was low at 3%. The most common complication was the occurrence of postoperative wound infection in 1.7%. CONCLUSION: It is possible to take a biopsy or surgically remove congenital nevi of different sizes even in infants. Serial excision of congenital nevi is an important tool for this purpose. In the investigated cohort, the complication rate was low. Histological confirmation is essential in case of clinically suspicious or atypical findings. Springer Medizin 2023-04-29 2023 /pmc/articles/PMC10290004/ /pubmed/37119200 http://dx.doi.org/10.1007/s00105-023-05147-0 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access Dieser Artikel wird unter der Creative Commons Namensnennung 4.0 International Lizenz veröffentlicht, welche die Nutzung, Vervielfältigung, Bearbeitung, Verbreitung und Wiedergabe in jeglichem Medium und Format erlaubt, sofern Sie den/die ursprünglichen Autor(en) und die Quelle ordnungsgemäß nennen, einen Link zur Creative Commons Lizenz beifügen und angeben, ob Änderungen vorgenommen wurden. Die in diesem Artikel enthaltenen Bilder und sonstiges Drittmaterial unterliegen ebenfalls der genannten Creative Commons Lizenz, sofern sich aus der Abbildungslegende nichts anderes ergibt. Sofern das betreffende Material nicht unter der genannten Creative Commons Lizenz steht und die betreffende Handlung nicht nach gesetzlichen Vorschriften erlaubt ist, ist für die oben aufgeführten Weiterverwendungen des Materials die Einwilligung des jeweiligen Rechteinhabers einzuholen. Weitere Details zur Lizenz entnehmen Sie bitte der Lizenzinformation auf http://creativecommons.org/licenses/by/4.0/deed.de (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Originalien
Kofler, Katrin
Häfner, Hans-Martin
Forchhammer, Stephan
Kofler, Lukas
Operative Therapie von Nävi bei Kindern in einem dermatochirurgischen Zentrum: Histopathologie und Komplikationen
title Operative Therapie von Nävi bei Kindern in einem dermatochirurgischen Zentrum: Histopathologie und Komplikationen
title_full Operative Therapie von Nävi bei Kindern in einem dermatochirurgischen Zentrum: Histopathologie und Komplikationen
title_fullStr Operative Therapie von Nävi bei Kindern in einem dermatochirurgischen Zentrum: Histopathologie und Komplikationen
title_full_unstemmed Operative Therapie von Nävi bei Kindern in einem dermatochirurgischen Zentrum: Histopathologie und Komplikationen
title_short Operative Therapie von Nävi bei Kindern in einem dermatochirurgischen Zentrum: Histopathologie und Komplikationen
title_sort operative therapie von nävi bei kindern in einem dermatochirurgischen zentrum: histopathologie und komplikationen
topic Originalien
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10290004/
https://www.ncbi.nlm.nih.gov/pubmed/37119200
http://dx.doi.org/10.1007/s00105-023-05147-0
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