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A review on the role of NDRG1 in different cancers
NDRG1 is a member of the α/β hydrolase superfamily that resides in the cytoplasm and participates in the stress responses, hormone response, cell growth, and differentiation. Several studies have pointed to the importance of NDRG1 in the carcinogenesis. This gene has been found to be up-regulated in...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10290039/ https://www.ncbi.nlm.nih.gov/pubmed/37249826 http://dx.doi.org/10.1007/s11033-023-08540-z |
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author | Ghafouri-Fard, Soudeh Ahmadi Teshnizi, Sara Hussen, Bashdar Mahmud Taheri, Mohammad Sharifi, Guive |
author_facet | Ghafouri-Fard, Soudeh Ahmadi Teshnizi, Sara Hussen, Bashdar Mahmud Taheri, Mohammad Sharifi, Guive |
author_sort | Ghafouri-Fard, Soudeh |
collection | PubMed |
description | NDRG1 is a member of the α/β hydrolase superfamily that resides in the cytoplasm and participates in the stress responses, hormone response, cell growth, and differentiation. Several studies have pointed to the importance of NDRG1 in the carcinogenesis. This gene has been found to be up-regulated in an array of cancer types such as bladder, esophageal squamous cell carcinoma, endometrial, lung and liver cancers, but being down-regulated in other types of cancers such as colorectal, gastric and ovarian cancers. The current study summarizes the evidence on the role of NDRG1 in the carcinogenic processes in different types of tissues. |
format | Online Article Text |
id | pubmed-10290039 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Springer Netherlands |
record_format | MEDLINE/PubMed |
spelling | pubmed-102900392023-06-25 A review on the role of NDRG1 in different cancers Ghafouri-Fard, Soudeh Ahmadi Teshnizi, Sara Hussen, Bashdar Mahmud Taheri, Mohammad Sharifi, Guive Mol Biol Rep Mini Review NDRG1 is a member of the α/β hydrolase superfamily that resides in the cytoplasm and participates in the stress responses, hormone response, cell growth, and differentiation. Several studies have pointed to the importance of NDRG1 in the carcinogenesis. This gene has been found to be up-regulated in an array of cancer types such as bladder, esophageal squamous cell carcinoma, endometrial, lung and liver cancers, but being down-regulated in other types of cancers such as colorectal, gastric and ovarian cancers. The current study summarizes the evidence on the role of NDRG1 in the carcinogenic processes in different types of tissues. Springer Netherlands 2023-05-30 2023 /pmc/articles/PMC10290039/ /pubmed/37249826 http://dx.doi.org/10.1007/s11033-023-08540-z Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Mini Review Ghafouri-Fard, Soudeh Ahmadi Teshnizi, Sara Hussen, Bashdar Mahmud Taheri, Mohammad Sharifi, Guive A review on the role of NDRG1 in different cancers |
title | A review on the role of NDRG1 in different cancers |
title_full | A review on the role of NDRG1 in different cancers |
title_fullStr | A review on the role of NDRG1 in different cancers |
title_full_unstemmed | A review on the role of NDRG1 in different cancers |
title_short | A review on the role of NDRG1 in different cancers |
title_sort | review on the role of ndrg1 in different cancers |
topic | Mini Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10290039/ https://www.ncbi.nlm.nih.gov/pubmed/37249826 http://dx.doi.org/10.1007/s11033-023-08540-z |
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