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Tau protein binds to the P53 E3 ubiquitin ligase MDM2

Tau gene mutations cause a progressive dementia and neurotoxic Tau forms deposited in neurofibrillary tangles are hallmarks of neurodegenerative tauopathies. Loss of non-canonical Tau functions may contribute to disease. In fact, Tau depletion affects the cellular response to DNA damage and tauopath...

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Detalles Bibliográficos
Autores principales:	Sola, Martina, Rendon-Angel, Azucena, Rojo Martinez, Viviana, Sgrignani, Jacopo, Magrin, Claudia, Piovesana, Ester, Cavalli, Andrea, Paganetti, Paolo, Papin, Stéphanie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10290082/ https://www.ncbi.nlm.nih.gov/pubmed/37353565 http://dx.doi.org/10.1038/s41598-023-37046-8

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