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Intracellular pH dynamics regulates intestinal stem cell lineage specification

Intracellular pH dynamics is increasingly recognized to regulate myriad cell behaviors. We report a finding that intracellular pH dynamics also regulates adult stem cell lineage specification. We identify an intracellular pH gradient in mouse small intestinal crypts, lowest in crypt stem cells and i...

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Detalles Bibliográficos
Autores principales:	Liu, Yi, Reyes, Efren, Castillo-Azofeifa, David, Klein, Ophir D., Nystul, Todd, Barber, Diane L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10290085/ https://www.ncbi.nlm.nih.gov/pubmed/37353491 http://dx.doi.org/10.1038/s41467-023-39312-9

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