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Coronary Artery Stenosis Severity in Patients With Different Coronary Artery Calcium Scores on Coronary Computed Tomography Angiography

Background In this study, we aimed to determine coronary artery stenosis severity in patients with different coronary artery calcium (CAC) scores. Methodology A total of 145 patients were included in the study. All patients were given beta-blockers 12 hours and two hours before the test to keep thei...

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Autores principales: Hashmi, Kashif A, Akhtar, Ammar, Masood, Farrukh, Maqbool, Shazia, Kabeer, Hafiz Muhammad Abdul, Ahmed, Jawad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10290215/
https://www.ncbi.nlm.nih.gov/pubmed/37362463
http://dx.doi.org/10.7759/cureus.39461
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author Hashmi, Kashif A
Akhtar, Ammar
Masood, Farrukh
Maqbool, Shazia
Kabeer, Hafiz Muhammad Abdul
Ahmed, Jawad
author_facet Hashmi, Kashif A
Akhtar, Ammar
Masood, Farrukh
Maqbool, Shazia
Kabeer, Hafiz Muhammad Abdul
Ahmed, Jawad
author_sort Hashmi, Kashif A
collection PubMed
description Background In this study, we aimed to determine coronary artery stenosis severity in patients with different coronary artery calcium (CAC) scores. Methodology A total of 145 patients were included in the study. All patients were given beta-blockers 12 hours and two hours before the test to keep their heart rate between 55 and 65 beats per minute. Computed tomography angiography was done from the pulmonary hilum up to the base of the heart and the patients were asked to hold their breath. The CAC score and stenosis were assessed. Results The mean age of the patients was 41.35 ± 4.95 years. In total, 112 (77.24%) patients were male and 33 (22.76%) were female. Regarding the frequency of the CAC score, a score of 0-9 was observed in 43 (29.66%) patients, 10-99 was observed in 55 (37.93%) patients, and 100-400 was observed in 47 (32.41%) patients. The CAC score was 0-9 in 86.4% of patients having normal coronary arteries. Two (5.2%) patients with a CAC score of 100-400 had mild coronary artery stenosis, 11 (32.3%) patients had moderate coronary artery disease, and 33 (66.0%) patients had severe coronary artery disease (p < 0.00001). Conclusions There is a strong association between CAC scores and the severity of coronary artery stenosis. A CAC score of zero is associated with a very low risk of having coronary artery stenosis.
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spelling pubmed-102902152023-06-25 Coronary Artery Stenosis Severity in Patients With Different Coronary Artery Calcium Scores on Coronary Computed Tomography Angiography Hashmi, Kashif A Akhtar, Ammar Masood, Farrukh Maqbool, Shazia Kabeer, Hafiz Muhammad Abdul Ahmed, Jawad Cureus Cardiology Background In this study, we aimed to determine coronary artery stenosis severity in patients with different coronary artery calcium (CAC) scores. Methodology A total of 145 patients were included in the study. All patients were given beta-blockers 12 hours and two hours before the test to keep their heart rate between 55 and 65 beats per minute. Computed tomography angiography was done from the pulmonary hilum up to the base of the heart and the patients were asked to hold their breath. The CAC score and stenosis were assessed. Results The mean age of the patients was 41.35 ± 4.95 years. In total, 112 (77.24%) patients were male and 33 (22.76%) were female. Regarding the frequency of the CAC score, a score of 0-9 was observed in 43 (29.66%) patients, 10-99 was observed in 55 (37.93%) patients, and 100-400 was observed in 47 (32.41%) patients. The CAC score was 0-9 in 86.4% of patients having normal coronary arteries. Two (5.2%) patients with a CAC score of 100-400 had mild coronary artery stenosis, 11 (32.3%) patients had moderate coronary artery disease, and 33 (66.0%) patients had severe coronary artery disease (p < 0.00001). Conclusions There is a strong association between CAC scores and the severity of coronary artery stenosis. A CAC score of zero is associated with a very low risk of having coronary artery stenosis. Cureus 2023-05-25 /pmc/articles/PMC10290215/ /pubmed/37362463 http://dx.doi.org/10.7759/cureus.39461 Text en Copyright © 2023, Hashmi et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Cardiology
Hashmi, Kashif A
Akhtar, Ammar
Masood, Farrukh
Maqbool, Shazia
Kabeer, Hafiz Muhammad Abdul
Ahmed, Jawad
Coronary Artery Stenosis Severity in Patients With Different Coronary Artery Calcium Scores on Coronary Computed Tomography Angiography
title Coronary Artery Stenosis Severity in Patients With Different Coronary Artery Calcium Scores on Coronary Computed Tomography Angiography
title_full Coronary Artery Stenosis Severity in Patients With Different Coronary Artery Calcium Scores on Coronary Computed Tomography Angiography
title_fullStr Coronary Artery Stenosis Severity in Patients With Different Coronary Artery Calcium Scores on Coronary Computed Tomography Angiography
title_full_unstemmed Coronary Artery Stenosis Severity in Patients With Different Coronary Artery Calcium Scores on Coronary Computed Tomography Angiography
title_short Coronary Artery Stenosis Severity in Patients With Different Coronary Artery Calcium Scores on Coronary Computed Tomography Angiography
title_sort coronary artery stenosis severity in patients with different coronary artery calcium scores on coronary computed tomography angiography
topic Cardiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10290215/
https://www.ncbi.nlm.nih.gov/pubmed/37362463
http://dx.doi.org/10.7759/cureus.39461
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