Cargando…

IsoAnalytics: a single-cell proteomics web server

MOTIVATION: Single-cell proteomics provide unprecedented resolution to examine biological processes. Customized data analysis and facile data visualization are crucial for scientific discovery. Further, user-friendly data analysis and visualization software that is easily accessible for the general...

Descripción completa

Detalles Bibliográficos
Autores principales: Palmer, Suzette N, Koh, Andrew Y, Zhan, Xiaowei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10290237/
https://www.ncbi.nlm.nih.gov/pubmed/37359721
http://dx.doi.org/10.1093/bioadv/vbad077
_version_ 1785062450605850624
author Palmer, Suzette N
Koh, Andrew Y
Zhan, Xiaowei
author_facet Palmer, Suzette N
Koh, Andrew Y
Zhan, Xiaowei
author_sort Palmer, Suzette N
collection PubMed
description MOTIVATION: Single-cell proteomics provide unprecedented resolution to examine biological processes. Customized data analysis and facile data visualization are crucial for scientific discovery. Further, user-friendly data analysis and visualization software that is easily accessible for the general scientific community is essential. RESULTS: We have created a web server, IsoAnalytics, that gives users without computational or bioinformatics background the ability to directly analyze and interactively visualize data obtained from the Isoplexis single cell technology platform. We envision this open-sourced web server will increase research productivity and serve as a free, competitive alternative for single-cell proteomics research. AVAILABILITY AND IMPLEMENTATION: IsoAnalytics is free and available at: https://cdc.biohpc.swmed.edu/isoplexis/ and is implemented in Python, with all major browsers supported. Code for IsoAnalytics is free and available at: https://github.com/zhanxw/Isoplexis_Data_Analysis. SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics Advances online.
format Online
Article
Text
id pubmed-10290237
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Oxford University Press
record_format MEDLINE/PubMed
spelling pubmed-102902372023-06-25 IsoAnalytics: a single-cell proteomics web server Palmer, Suzette N Koh, Andrew Y Zhan, Xiaowei Bioinform Adv Application Note MOTIVATION: Single-cell proteomics provide unprecedented resolution to examine biological processes. Customized data analysis and facile data visualization are crucial for scientific discovery. Further, user-friendly data analysis and visualization software that is easily accessible for the general scientific community is essential. RESULTS: We have created a web server, IsoAnalytics, that gives users without computational or bioinformatics background the ability to directly analyze and interactively visualize data obtained from the Isoplexis single cell technology platform. We envision this open-sourced web server will increase research productivity and serve as a free, competitive alternative for single-cell proteomics research. AVAILABILITY AND IMPLEMENTATION: IsoAnalytics is free and available at: https://cdc.biohpc.swmed.edu/isoplexis/ and is implemented in Python, with all major browsers supported. Code for IsoAnalytics is free and available at: https://github.com/zhanxw/Isoplexis_Data_Analysis. SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics Advances online. Oxford University Press 2023-06-21 /pmc/articles/PMC10290237/ /pubmed/37359721 http://dx.doi.org/10.1093/bioadv/vbad077 Text en © The Author(s) 2023. Published by Oxford University Press. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Application Note
Palmer, Suzette N
Koh, Andrew Y
Zhan, Xiaowei
IsoAnalytics: a single-cell proteomics web server
title IsoAnalytics: a single-cell proteomics web server
title_full IsoAnalytics: a single-cell proteomics web server
title_fullStr IsoAnalytics: a single-cell proteomics web server
title_full_unstemmed IsoAnalytics: a single-cell proteomics web server
title_short IsoAnalytics: a single-cell proteomics web server
title_sort isoanalytics: a single-cell proteomics web server
topic Application Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10290237/
https://www.ncbi.nlm.nih.gov/pubmed/37359721
http://dx.doi.org/10.1093/bioadv/vbad077
work_keys_str_mv AT palmersuzetten isoanalyticsasinglecellproteomicswebserver
AT kohandrewy isoanalyticsasinglecellproteomicswebserver
AT zhanxiaowei isoanalyticsasinglecellproteomicswebserver