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IsoAnalytics: a single-cell proteomics web server
MOTIVATION: Single-cell proteomics provide unprecedented resolution to examine biological processes. Customized data analysis and facile data visualization are crucial for scientific discovery. Further, user-friendly data analysis and visualization software that is easily accessible for the general...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10290237/ https://www.ncbi.nlm.nih.gov/pubmed/37359721 http://dx.doi.org/10.1093/bioadv/vbad077 |
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author | Palmer, Suzette N Koh, Andrew Y Zhan, Xiaowei |
author_facet | Palmer, Suzette N Koh, Andrew Y Zhan, Xiaowei |
author_sort | Palmer, Suzette N |
collection | PubMed |
description | MOTIVATION: Single-cell proteomics provide unprecedented resolution to examine biological processes. Customized data analysis and facile data visualization are crucial for scientific discovery. Further, user-friendly data analysis and visualization software that is easily accessible for the general scientific community is essential. RESULTS: We have created a web server, IsoAnalytics, that gives users without computational or bioinformatics background the ability to directly analyze and interactively visualize data obtained from the Isoplexis single cell technology platform. We envision this open-sourced web server will increase research productivity and serve as a free, competitive alternative for single-cell proteomics research. AVAILABILITY AND IMPLEMENTATION: IsoAnalytics is free and available at: https://cdc.biohpc.swmed.edu/isoplexis/ and is implemented in Python, with all major browsers supported. Code for IsoAnalytics is free and available at: https://github.com/zhanxw/Isoplexis_Data_Analysis. SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics Advances online. |
format | Online Article Text |
id | pubmed-10290237 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-102902372023-06-25 IsoAnalytics: a single-cell proteomics web server Palmer, Suzette N Koh, Andrew Y Zhan, Xiaowei Bioinform Adv Application Note MOTIVATION: Single-cell proteomics provide unprecedented resolution to examine biological processes. Customized data analysis and facile data visualization are crucial for scientific discovery. Further, user-friendly data analysis and visualization software that is easily accessible for the general scientific community is essential. RESULTS: We have created a web server, IsoAnalytics, that gives users without computational or bioinformatics background the ability to directly analyze and interactively visualize data obtained from the Isoplexis single cell technology platform. We envision this open-sourced web server will increase research productivity and serve as a free, competitive alternative for single-cell proteomics research. AVAILABILITY AND IMPLEMENTATION: IsoAnalytics is free and available at: https://cdc.biohpc.swmed.edu/isoplexis/ and is implemented in Python, with all major browsers supported. Code for IsoAnalytics is free and available at: https://github.com/zhanxw/Isoplexis_Data_Analysis. SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics Advances online. Oxford University Press 2023-06-21 /pmc/articles/PMC10290237/ /pubmed/37359721 http://dx.doi.org/10.1093/bioadv/vbad077 Text en © The Author(s) 2023. Published by Oxford University Press. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Application Note Palmer, Suzette N Koh, Andrew Y Zhan, Xiaowei IsoAnalytics: a single-cell proteomics web server |
title | IsoAnalytics: a single-cell proteomics web server |
title_full | IsoAnalytics: a single-cell proteomics web server |
title_fullStr | IsoAnalytics: a single-cell proteomics web server |
title_full_unstemmed | IsoAnalytics: a single-cell proteomics web server |
title_short | IsoAnalytics: a single-cell proteomics web server |
title_sort | isoanalytics: a single-cell proteomics web server |
topic | Application Note |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10290237/ https://www.ncbi.nlm.nih.gov/pubmed/37359721 http://dx.doi.org/10.1093/bioadv/vbad077 |
work_keys_str_mv | AT palmersuzetten isoanalyticsasinglecellproteomicswebserver AT kohandrewy isoanalyticsasinglecellproteomicswebserver AT zhanxiaowei isoanalyticsasinglecellproteomicswebserver |