Free-fatty acid receptor-1 (FFA1/GPR40) promotes papillary RCC proliferation and tumor growth via Src/PI3K/AKT/NF-κB but suppresses migration by inhibition of EGFR, ERK1/2, STAT3 and EMT

BACKGROUND: Papillary renal cell carcinoma (pRCC) is a highly metastatic genitourinary cancer and is generally irresponsive to common treatments used for the more prevalent clear-cell (ccRCC) subtype. The goal of this study was to examine the novel role of the free fatty-acid receptor-1 (FFA1/GPR40)...

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Detalles Bibliográficos
Autores principales: Karmokar, Priyanka F., Moniri, Nader H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10290327/
https://www.ncbi.nlm.nih.gov/pubmed/37355607
http://dx.doi.org/10.1186/s12935-023-02967-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10290327/
https://www.ncbi.nlm.nih.gov/pubmed/37355607
http://dx.doi.org/10.1186/s12935-023-02967-x

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