2-phenylacetamide Separated from the seed of Lepidium apetalum Willd. inhibited renal fibrosis via MAPK pathway mediated RAAS and oxidative stress in SHR Rats

BACKGROUND: Renal fibrosis with Renin–angiotensin–aldosterone system (RAAS) activation and oxidative stress are one of the major complications in hypertension. 2-phenylacetamide (PA), a major active component of Lepidium apetalum Willd. (L.A), has numerous pharmacological effects. Its analogues have...

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Detalles Bibliográficos
Autores principales: Yuan, Pei-pei, Li, Meng, Zhang, Qi, Zeng, Meng-nan, Ke, Ying-ying, Wei, Ya-xin, Fu, Yang, Zheng, Xiao-ke, Feng, Wei-sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10290354/
https://www.ncbi.nlm.nih.gov/pubmed/37353787
http://dx.doi.org/10.1186/s12906-023-04012-w

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