Cargando…

Shared genetic architecture between mental health and the brain functional connectome in the UK Biobank

Psychiatric disorders are complex clinical conditions with large heterogeneity and overlap in symptoms, genetic liability and brain imaging abnormalities. Building on a dimensional conceptualization of mental health, previous studies have reported genetic overlap between psychiatric disorders and po...

Descripción completa

Detalles Bibliográficos
Autores principales:	Roelfs, Daniel, Frei, Oleksandr, van der Meer, Dennis, Tissink, Elleke, Shadrin, Alexey, Alnaes, Dag, Andreassen, Ole A., Westlye, Lars T., Kaufmann, Tobias
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10290393/ https://www.ncbi.nlm.nih.gov/pubmed/37353766 http://dx.doi.org/10.1186/s12888-023-04905-7

Ejemplares similares

Phenotypically independent profiles relevant to mental health are genetically correlated
por: Roelfs, Daniel, et al.
Publicado: (2021)

The genetic architecture of human cortical folding
por: van der Meer, Dennis, et al.
Publicado: (2021)

Association between complement component 4A expression, cognitive performance and brain imaging measures in UK Biobank
por: O'Connell, Kevin S., et al.
Publicado: (2022)

No signs of neurodegenerative effects in 15q11.2 BP1-BP2 copy number variant carriers in the UK Biobank
por: Boen, Rune, et al.
Publicado: (2023)

Distributed genetic architecture across the hippocampal formation implies common neuropathology across brain disorders
por: Bahrami, Shahram, et al.
Publicado: (2022)

The genetic architecture of the human thalamus and its overlap with ten common brain disorders
por: Elvsåshagen, Torbjørn, et al.
Publicado: (2021)

Fast qualitY conTrol meThod foR derIved diffUsion Metrics (YTTRIUM) in big data analysis: U.K. Biobank 18,608 example
por: Maximov, Ivan I., et al.
Publicado: (2021)

Towards an optimised processing pipeline for diffusion magnetic resonance imaging data: Effects of artefact corrections on diffusion metrics and their age associations in UK Biobank
por: Maximov, Ivan I., et al.
Publicado: (2019)

Differences in directed functional brain connectivity related to age, sex and mental health
por: Lund, Martina J., et al.
Publicado: (2020)

Shared genetic architecture between neuroticism, coronary artery disease and cardiovascular risk factors
por: Torgersen, Kristin, et al.
Publicado: (2021)

Genetic Overlap Between Alzheimer’s Disease and Depression Mapped Onto the Brain
por: Monereo-Sánchez, Jennifer, et al.
Publicado: (2021)

Oxytocin pathway gene networks in the human brain
por: Quintana, Daniel S., et al.
Publicado: (2019)

Author Correction: Understanding the genetic determinants of the brain with MOSTest
por: van der Meer, Dennis, et al.
Publicado: (2020)

Understanding the genetic determinants of the brain with MOSTest
por: van der Meer, Dennis, et al.
Publicado: (2020)

Genetic architecture of brain age and its causal relations with brain and mental disorders
por: Leonardsen, Esten H., et al.
Publicado: (2023)

The shared genetic risk architecture of neurological and psychiatric disorders: a genome-wide analysis
por: Smeland, Olav B., et al.
Publicado: (2023)

Functional connectivity directionality between large-scale resting-state networks across typical and non-typical trajectories in children and adolescence
por: Lund, Martina J., et al.
Publicado: (2022)

Quantifying the Polygenic Architecture of the Human Cerebral Cortex: Extensive Genetic Overlap between Cortical Thickness and Surface Area
por: van der Meer, Dennis, et al.
Publicado: (2020)

Shared genetic architecture of blood eosinophil counts and asthma in UK Biobank
por: Li, Boyang, et al.
Publicado: (2023)

Testing relationships between multimodal modes of brain structural variation and age, sex and polygenic scores for neuroticism in children and adolescents
por: Norbom, Linn B., et al.
Publicado: (2020)

Brain age prediction using fMRI network coupling in youths and associations with psychiatric symptoms
por: Lund, Martina J., et al.
Publicado: (2021)

Bio-psycho-social factors’ associations with brain age: a large-scale UK Biobank diffusion study of 35,749 participants
por: Korbmacher, Max, et al.
Publicado: (2023)

Shared pattern of impaired social communication and cognitive ability in the youth brain across diagnostic boundaries
por: Voldsbekk, Irene, et al.
Publicado: (2023)

Sex‐ and age‐specific associations between cardiometabolic risk and white matter brain age in the UK Biobank cohort
por: Subramaniapillai, Sivaniya, et al.
Publicado: (2022)

Oxytocin-pathway polygenic scores for severe mental disorders and metabolic phenotypes in the UK Biobank
por: Winterton, Adriano, et al.
Publicado: (2021)

Shared genetic architecture between irritable bowel syndrome and psychiatric disorders reveals molecular pathways of the gut-brain axis
por: Tesfaye, Markos, et al.
Publicado: (2023)

Maturation of cortical microstructure and cognitive development in childhood and adolescence: A T1w/T2w ratio MRI study
por: Norbom, Linn B., et al.
Publicado: (2020)

Population-based body–brain mapping links brain morphology with anthropometrics and body composition
por: Gurholt, Tiril P., et al.
Publicado: (2021)

Reduced load-dependent default mode network deactivation across executive tasks in schizophrenia spectrum disorders
por: Haatveit, Beathe, et al.
Publicado: (2016)

Genome-wide Association Analysis of Schizophrenia and Vitamin D Levels Shows Shared Genetic Architecture and Identifies Novel Risk Loci
por: Jaholkowski, Piotr, et al.
Publicado: (2023)

Shared genetic loci between depression and cardiometabolic traits
por: Torgersen, Kristin, et al.
Publicado: (2022)

Characterising the shared genetic determinants of bipolar disorder, schizophrenia and risk-taking
por: Hindley, Guy, et al.
Publicado: (2021)

Brain connectivity aberrations in anabolic-androgenic steroid users
por: Westlye, Lars T., et al.
Publicado: (2016)

Functional connectivity in multiple sclerosis modelled as connectome stability: A 5-year follow-up study
por: Høgestøl, Einar August, et al.
Publicado: (2021)

Delineating disorder-general and disorder-specific dimensions of psychopathology from functional brain networks in a developmental clinical sample
por: Voldsbekk, Irene, et al.
Publicado: (2023)

Key Brain Network Nodes Show Differential Cognitive Relevance and Developmental Trajectories during Childhood and Adolescence
por: Kolskår, Knut K., et al.
Publicado: (2018)

The link between liver fat and cardiometabolic diseases is highlighted by genome-wide association study of MRI-derived measures of body composition
por: van der Meer, Dennis, et al.
Publicado: (2022)

Mapping Normative Trajectories of Cognitive Function and Its Relation to Psychopathology Symptoms and Genetic Risk in Youth
por: Kjelkenes, Rikka, et al.
Publicado: (2022)

Comparing empirical kinship derived heritability for imaging genetics traits in the UK biobank and human connectome project
por: Gao, Si, et al.
Publicado: (2021)

Associations between reproductive history, hormone use, APOE ε4 genotype and cognition in middle- to older-aged women from the UK Biobank
por: Lindseth, Linn R. S., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_9nm27a12ou202oevirs246ht2h