Phellodendronoside A Exerts Anticancer Effects Depending on Inducing Apoptosis Through ROS/Nrf2/Notch Pathway and Modulating Metabolite Profiles in Hepatocellular Carcinoma

PURPOSE: To reveal the potential mechanism of PDA on hepatocellular carcinoma SMMC-7721 cells in vitro. METHODS: The cytotoxic activity, colony formation, cell cycle distribution, apoptosis and their associated protein analysis, intracellular reactive oxygen species (ROS) and Ca(2+) levels, proteins...

Descripción completa

Detalles Bibliográficos
Autores principales: Si, Yanpo, Hui, Chengcheng, Guo, Tao, Liu, Mengqi, Chen, Xiaohui, Dong, Chunhong, Feng, Shuying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10290457/
https://www.ncbi.nlm.nih.gov/pubmed/37361906
http://dx.doi.org/10.2147/JHC.S403630

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10290457/
https://www.ncbi.nlm.nih.gov/pubmed/37361906
http://dx.doi.org/10.2147/JHC.S403630

Ejemplares similares