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Phellodendronoside A Exerts Anticancer Effects Depending on Inducing Apoptosis Through ROS/Nrf2/Notch Pathway and Modulating Metabolite Profiles in Hepatocellular Carcinoma
PURPOSE: To reveal the potential mechanism of PDA on hepatocellular carcinoma SMMC-7721 cells in vitro. METHODS: The cytotoxic activity, colony formation, cell cycle distribution, apoptosis and their associated protein analysis, intracellular reactive oxygen species (ROS) and Ca(2+) levels, proteins...
Autores principales: | Si, Yanpo, Hui, Chengcheng, Guo, Tao, Liu, Mengqi, Chen, Xiaohui, Dong, Chunhong, Feng, Shuying |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10290457/ https://www.ncbi.nlm.nih.gov/pubmed/37361906 http://dx.doi.org/10.2147/JHC.S403630 |
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