Dynamic heterogeneity of colorectal cancer during progression revealed clinical risk-associated cell types and regulations in single-cell resolution and spatial context

BACKGROUND: Tumor heterogeneity is contributed by tumor cells and the microenvironment. Dynamics of tumor heterogeneity during colorectal cancer (CRC) progression have not been elucidated. METHODS: Eight single-cell RNA sequencing (scRNA-seq) data sets of CRC were included. Milo was utilized to reve...

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Detalles Bibliográficos
Autores principales: Ke, Haoxian, Li, Zhihao, Li, Peisi, Ye, Shubiao, Huang, Junfeng, Hu, Tuo, Zhang, Chi, Yuan, Ming, Chen, Yuan, Wu, Xianrui, Lan, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10290555/
https://www.ncbi.nlm.nih.gov/pubmed/37360193
http://dx.doi.org/10.1093/gastro/goad034

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