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Levofloxacin-Induced Toxic Epidermal Necrolysis

Toxic epidermal necrolysis (TEN), also known as Lyell's syndrome, is a severe episodic mucocutaneous reaction that is usually brought on by oral medications and/or sporadically by infections. We report a case of a 19-year-old male with the presenting complaint of generalized skin blistering ove...

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Autores principales: Khan, Andeebia A, Aisha, Urwah, Hassan, Abdullah, Haider, Zaroon, Cook, Daniel E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10290569/
https://www.ncbi.nlm.nih.gov/pubmed/37366440
http://dx.doi.org/10.7759/cureus.39504
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author Khan, Andeebia A
Aisha, Urwah
Hassan, Abdullah
Haider, Zaroon
Cook, Daniel E
author_facet Khan, Andeebia A
Aisha, Urwah
Hassan, Abdullah
Haider, Zaroon
Cook, Daniel E
author_sort Khan, Andeebia A
collection PubMed
description Toxic epidermal necrolysis (TEN), also known as Lyell's syndrome, is a severe episodic mucocutaneous reaction that is usually brought on by oral medications and/or sporadically by infections. We report a case of a 19-year-old male with the presenting complaint of generalized skin blistering over the previous seven days at the dermatology outpatient clinic. The patient has had epilepsy since he was 10 years old. Due to an upper respiratory tract illness, a local healthcare facility recommended oral levofloxacin to him seven days ago. Levofloxacin-induced toxic epidermal necrolysis (TEN) was suspected based on the patient's medical history, physical examination, and research. On the basis of histological investigations and clinical correlation, the diagnosis of TEN was determined. The mainstay of treatment after diagnosis was made was supportive care. The best methods for treating TEN involve stopping any potential causal agents and providing supportive care. The patient received care in the intensive care unit.
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spelling pubmed-102905692023-06-26 Levofloxacin-Induced Toxic Epidermal Necrolysis Khan, Andeebia A Aisha, Urwah Hassan, Abdullah Haider, Zaroon Cook, Daniel E Cureus Dermatology Toxic epidermal necrolysis (TEN), also known as Lyell's syndrome, is a severe episodic mucocutaneous reaction that is usually brought on by oral medications and/or sporadically by infections. We report a case of a 19-year-old male with the presenting complaint of generalized skin blistering over the previous seven days at the dermatology outpatient clinic. The patient has had epilepsy since he was 10 years old. Due to an upper respiratory tract illness, a local healthcare facility recommended oral levofloxacin to him seven days ago. Levofloxacin-induced toxic epidermal necrolysis (TEN) was suspected based on the patient's medical history, physical examination, and research. On the basis of histological investigations and clinical correlation, the diagnosis of TEN was determined. The mainstay of treatment after diagnosis was made was supportive care. The best methods for treating TEN involve stopping any potential causal agents and providing supportive care. The patient received care in the intensive care unit. Cureus 2023-05-25 /pmc/articles/PMC10290569/ /pubmed/37366440 http://dx.doi.org/10.7759/cureus.39504 Text en Copyright © 2023, Khan et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Dermatology
Khan, Andeebia A
Aisha, Urwah
Hassan, Abdullah
Haider, Zaroon
Cook, Daniel E
Levofloxacin-Induced Toxic Epidermal Necrolysis
title Levofloxacin-Induced Toxic Epidermal Necrolysis
title_full Levofloxacin-Induced Toxic Epidermal Necrolysis
title_fullStr Levofloxacin-Induced Toxic Epidermal Necrolysis
title_full_unstemmed Levofloxacin-Induced Toxic Epidermal Necrolysis
title_short Levofloxacin-Induced Toxic Epidermal Necrolysis
title_sort levofloxacin-induced toxic epidermal necrolysis
topic Dermatology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10290569/
https://www.ncbi.nlm.nih.gov/pubmed/37366440
http://dx.doi.org/10.7759/cureus.39504
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