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Myasthenia Gravis Associated With COVID-19 Infection

COVID-19 first emerged in Wuhan, China in late December 2019. The disease majorly involves the lungs leading to various respiratory complications; however, neurological manifestations of the disease are also described in the literature. Here, we report a case of COVID-19-induced seronegative myasthe...

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Autores principales: Sadiq, Waleed, Waleed, Madeeha Subhan, Rizvi, Taqi A, Khan, Shahkar, El Hage, Halim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10290576/
https://www.ncbi.nlm.nih.gov/pubmed/37366447
http://dx.doi.org/10.7759/cureus.39506
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author Sadiq, Waleed
Waleed, Madeeha Subhan
Rizvi, Taqi A
Khan, Shahkar
El Hage, Halim
author_facet Sadiq, Waleed
Waleed, Madeeha Subhan
Rizvi, Taqi A
Khan, Shahkar
El Hage, Halim
author_sort Sadiq, Waleed
collection PubMed
description COVID-19 first emerged in Wuhan, China in late December 2019. The disease majorly involves the lungs leading to various respiratory complications; however, neurological manifestations of the disease are also described in the literature. Here, we report a case of COVID-19-induced seronegative myasthenia gravis (MG). We discuss the cases of COVID-19 and MG already described in the literature in regard to their presentation and serological findings to better understand the association between the two disease processes. MG may be missed in patients after COVID-19 infections because of the comorbidities and anti-acetylcholine receptor and anti-muscle-specific tyrosine kinase antibodies being negative. Evidence from more studies will help analyze the pathological timeline of the disease process and the immunological characteristics of COVID-19-induced MG which can prove to have morbidity and mortality benefit in patients with COVID-19-induced MG.
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spelling pubmed-102905762023-06-26 Myasthenia Gravis Associated With COVID-19 Infection Sadiq, Waleed Waleed, Madeeha Subhan Rizvi, Taqi A Khan, Shahkar El Hage, Halim Cureus Internal Medicine COVID-19 first emerged in Wuhan, China in late December 2019. The disease majorly involves the lungs leading to various respiratory complications; however, neurological manifestations of the disease are also described in the literature. Here, we report a case of COVID-19-induced seronegative myasthenia gravis (MG). We discuss the cases of COVID-19 and MG already described in the literature in regard to their presentation and serological findings to better understand the association between the two disease processes. MG may be missed in patients after COVID-19 infections because of the comorbidities and anti-acetylcholine receptor and anti-muscle-specific tyrosine kinase antibodies being negative. Evidence from more studies will help analyze the pathological timeline of the disease process and the immunological characteristics of COVID-19-induced MG which can prove to have morbidity and mortality benefit in patients with COVID-19-induced MG. Cureus 2023-05-25 /pmc/articles/PMC10290576/ /pubmed/37366447 http://dx.doi.org/10.7759/cureus.39506 Text en Copyright © 2023, Sadiq et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Sadiq, Waleed
Waleed, Madeeha Subhan
Rizvi, Taqi A
Khan, Shahkar
El Hage, Halim
Myasthenia Gravis Associated With COVID-19 Infection
title Myasthenia Gravis Associated With COVID-19 Infection
title_full Myasthenia Gravis Associated With COVID-19 Infection
title_fullStr Myasthenia Gravis Associated With COVID-19 Infection
title_full_unstemmed Myasthenia Gravis Associated With COVID-19 Infection
title_short Myasthenia Gravis Associated With COVID-19 Infection
title_sort myasthenia gravis associated with covid-19 infection
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10290576/
https://www.ncbi.nlm.nih.gov/pubmed/37366447
http://dx.doi.org/10.7759/cureus.39506
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