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Enyne acetogenins from Porcelia macrocarpa displayed anti-Trypanosoma cruzi activity and cause a reduction in the intracellular calcium level
Natural products are a promising source of new compounds with a wide spectrum of pharmacological properties, including antiprotozoal activities. Chagas disease, caused by the protozoan parasite Trypanosoma cruzi, is one of several neglected tropical diseases with reduced options for treatment, which...
Autores principales: | Thevenard, Fernanda, Brito, Ivanildo A., Costa-Silva, Thais A., Tempone, Andre G., Lago, João Henrique G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10290671/ https://www.ncbi.nlm.nih.gov/pubmed/37355735 http://dx.doi.org/10.1038/s41598-023-37520-3 |
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