A PPIX-binding probe facilitates discovery of PPIX-induced cell death modulation by peroxiredoxin

While heme synthesis requires the formation of a potentially lethal intermediate, protoporphyrin IX (PPIX), surprisingly little is known about the mechanism of its toxicity, aside from its phototoxicity. The cellular protein interactions of PPIX might provide insight into modulators of PPIX-induced...

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Detalles Bibliográficos
Autores principales: Lynch, John, Wang, Yao, Li, Yuxin, Kavdia, Kanisha, Fukuda, Yu, Ranjit, Sabina, Robinson, Camenzind G., Grace, Christy R., Xia, Youlin, Peng, Junmin, Schuetz, John D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10290680/
https://www.ncbi.nlm.nih.gov/pubmed/37355765
http://dx.doi.org/10.1038/s42003-023-05024-5

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