Silencing of TRAF5 enhances necroptosis in hepatocellular carcinoma by inhibiting LTBR-mediated NF-κB signaling

BACKGROUND: Hepatocellular carcinoma (HCC) is a common malignancy with poor prognosis and high mortality. This study aimed to explore the oncogenic mechanisms of TRAF5 in HCC and provide a novel therapeutic strategy for HCC. METHODS: Human HCC cell lines (HepG2, HuH7, SMMC-LM3, and Hep3B), normal ad...

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Detalles Bibliográficos
Autores principales: Wu, Guolin, Wu, Fangping, Zhou, Yang Qing, Lu, Wenwen, Hu, Feng Lin, Fan, Xiaofen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2023
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10290833/
https://www.ncbi.nlm.nih.gov/pubmed/37366426
http://dx.doi.org/10.7717/peerj.15551

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10290833/
https://www.ncbi.nlm.nih.gov/pubmed/37366426
http://dx.doi.org/10.7717/peerj.15551

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