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Wnt signaling preserves progenitor cell multipotency during adipose tissue development

Mesenchymal stem/progenitor cells are essential for tissue development and repair throughout life, but how they are maintained under chronic differentiation pressure is not known. Using single-cell transcriptomics of human progenitor cells we find that adipose differentiation stimuli elicit two cell...

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Detalles Bibliográficos
Autores principales: Yang Loureiro, Zinger, Joyce, Shannon, DeSouza, Tiffany, Solivan-Rivera, Javier, Desai, Anand, Skritakis, Pantos, Yang, Qin, Ziegler, Rachel, Zhong, Denise, Nguyen, Tammy T., MacDougald, Ormond A., Corvera, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10290956/
https://www.ncbi.nlm.nih.gov/pubmed/37337125
http://dx.doi.org/10.1038/s42255-023-00813-y