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UBE2C expression is elevated in hepatoblastoma and correlates with inferior patient survival

Hepatoblastoma (HB) is the most common malignant liver tumor among children. To gain insight into the pathobiology of HB, we performed RNA sequence analysis on 5 patient-derived xenograft lines (HB-243, HB-279, HB-282, HB-284, HB-295) and 1 immortalized cell line (HUH6). Using cultured hepatocytes a...

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Detalles Bibliográficos
Autores principales: Nousiainen, Ruth, Eloranta, Katja, Isoaho, Noora, Cairo, Stefano, Wilson, David B., Heikinheimo, Markku, Pihlajoki, Marjut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10291054/
https://www.ncbi.nlm.nih.gov/pubmed/37377594
http://dx.doi.org/10.3389/fgene.2023.1170940