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EZH1/2 dual inhibitors suppress HTLV-1-infected cell proliferation and hyperimmune response in HTLV-1-associated myelopathy
BACKGROUND: Human T-cell leukemia virus type 1 (HTLV-1) causes HTLV-1-associated myelopathy (HAM), adult T-cell leukemia/lymphoma (ATL), HTLV-1-associated uveitis, and pulmonary diseases. Although both HAM and ATL show proliferation of infected cells, their pathogeneses are quite different. In parti...
Autores principales: | Koseki, Akihito, Araya, Natsumi, Yamagishi, Makoto, Yamauchi, Junji, Yagishita, Naoko, Takao, Naoki, Takahashi, Katsunori, Kunitomo, Yasuo, Honma, Daisuke, Araki, Kazushi, Uchimaru, Kaoru, Sato, Tomoo, Yamano, Yoshihisa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10291084/ https://www.ncbi.nlm.nih.gov/pubmed/37378292 http://dx.doi.org/10.3389/fmicb.2023.1175762 |
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