Iron-mediated oxidative stress induces PD-L1 expression via activation of c-Myc in lung adenocarcinoma

Introduction: The PD-1/PD-L1 axis is hijacked by lung adenocarcinoma (LUAD) cells to escape immune surveillance. PD-L1 expression in LUAD is affected, among others, by the metabolic trafficking between tumor cells and the tumor microenvironment (TME). Methods: Correlation between PD-L1 expression an...

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Detalles Bibliográficos
Autores principales: Battaglia, Anna Martina, Sacco, Alessandro, Aversa, Ilenia, Santamaria, Gianluca, Palmieri, Camillo, Botta, Cirino, De Stefano, Roberto, Bitetto, Maurizio, Petriaggi, Lavinia, Giorgio, Emanuele, Faniello, Concetta Maria, Costanzo, Francesco, Biamonte, Flavia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10291098/
https://www.ncbi.nlm.nih.gov/pubmed/37377735
http://dx.doi.org/10.3389/fcell.2023.1208485

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