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Early in vitro evidence indicates that deacetylated sialic acids modulate multi-drug resistance in colon and lung cancers via breast cancer resistance protein

Cancers utilize sugar residues to engage in multidrug resistance. The underlying mechanism of action involving glycans, specifically the glycan sialic acid (Sia) and its various functional group alterations, has not been explored. ATP-binding cassette (ABC) transporter proteins, key proteins utilize...

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Detalles Bibliográficos
Autores principales: Tuffour, Isaac, Amuzu, Setor, Bayoumi, Hala, Surtaj, Iram, Parrish, Colin, Willand-Charnley, Rachel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10291187/
https://www.ncbi.nlm.nih.gov/pubmed/37377914
http://dx.doi.org/10.3389/fonc.2023.1145333