Cargando…

Variants in JAZF1 are associated with asthma, type 2 diabetes, and height in the United Kingdom biobank population

Background: Asthma, type 2 diabetes (T2D), and anthropometric measures are correlated complex traits that all have a major genetic component. Objective: To investigate the overlap in genetic variants associated with these complex traits. Methods: Using United Kingdom Biobank data, we performed univa...

Descripción completa

Detalles Bibliográficos
Autores principales:	DeWan, Andrew T., Cahill, Megan E., Cornejo-Sanchez, Diana M., Li, Yining, Dong, Zihan, Fabiha, Tabassum, Sun, Hao, Wang, Gao, Leal, Suzanne M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10291233/ https://www.ncbi.nlm.nih.gov/pubmed/37377600 http://dx.doi.org/10.3389/fgene.2023.1129389

Ejemplares similares

Polygenic Scores and Parental Predictors: An Adult Height Study Based on the United Kingdom Biobank and the Framingham Heart Study
por: You, Chong, et al.
Publicado: (2021)

The genetic contribution of the X chromosome in age-related hearing loss
por: Naderi, Elnaz, et al.
Publicado: (2023)

The influence of childhood asthma on adult height: evidence from the UK Biobank
por: Chen, Wenwen, et al.
Publicado: (2022)

Recent advances and challenges of rare variant association analysis in the biobank sequencing era
por: Chen, Wenan, et al.
Publicado: (2022)

Prevalence of Fabry disease-causing variants in the UK Biobank
por: Gilchrist, Mark, et al.
Publicado: (2023)

Practice variation across consent templates for biobank research. a survey of German biobanks
por: Hirschberg, Irene, et al.
Publicado: (2013)

Association of the JAZF1 Variant in Adults With a Parental History of Type 2 Diabetes Mellitus In Pakistan
por: Zano, Sheh, et al.
Publicado: (2020)

New insights into the suppression of inflammation and lipid accumulation by JAZF1
por: Chen, Wujun, et al.
Publicado: (2022)

JAZF1/SUZ12 gene fusion in endometrial stromal sarcomas
por: Hrzenjak, Andelko
Publicado: (2016)

Jazf1 promotes prostate cancer progression by activating JNK/Slug
por: Sung, Yonghun, et al.
Publicado: (2017)

Identification of Novel Genetic Variants and Comorbidities Associated With ICD-10-Based Diagnosis of Hypertrophic Cardiomyopathy Using the UK Biobank Cohort
por: Gyftopoulos, Alex, et al.
Publicado: (2022)

Sequence variant analysis of RNA sequences in severe equine asthma
por: Tessier, Laurence, et al.
Publicado: (2018)

Genetics of Tinnitus: Time to Biobank Phantom Sounds
por: Cederroth, Christopher R., et al.
Publicado: (2017)

A leap of faith: building the trust in human biobanks
por: Zhang, Yi, et al.
Publicado: (2023)

JAZF1 heterozygous knockout mice show altered adipose development and metabolism
por: Jeong, Jain, et al.
Publicado: (2021)

JAZF1: A Metabolic Regulator of Sensitivity to a Polyamine-Targeted Therapy
por: Rosario, Spencer R., et al.
Publicado: (2023)

Association of JAZF1 and TSPAN8/LGR5 variants in relation to type 2 diabetes mellitus in a Saudi population
por: Alharbi, Khalid Khalaf, et al.
Publicado: (2015)

Deliberations About Genomic Research and Biobanks With Citizens of the Chickasaw Nation
por: Reedy, Justin, et al.
Publicado: (2020)

Subsampling Technique to Estimate Variance Component for UK-Biobank Traits
por: Xu, Ting, et al.
Publicado: (2021)

Editorial: Current Status and Future Challenges of Biobank Data Analysis
por: Lu, Tzu-Pin, et al.
Publicado: (2022)

Reduced signal for polygenic adaptation of height in UK Biobank
por: Berg, Jeremy J, et al.
Publicado: (2019)

Association Testing of Novel Type 2 Diabetes Risk Alleles in the JAZF1, CDC123/CAMK1D, TSPAN8, THADA, ADAMTS9, and NOTCH2 Loci With Insulin Release, Insulin Sensitivity, and Obesity in a Population-Based Sample of 4,516 Glucose-Tolerant Middle-Aged Danes
por: Grarup, Niels, et al.
Publicado: (2008)

Relationship among genetic variants, obesity traits and asthma in the Taiwan Biobank
por: Huang, Ying-Jhen, et al.
Publicado: (2022)

Construction of lncRNA-Mediated Competing Endogenous RNA Networks Correlated With T2 Asthma
por: Wang, Zihan, et al.
Publicado: (2022)

Fank1 and Jazf1 promote multiciliated cell differentiation in the mouse airway epithelium
por: Johnson, Jo-Anne, et al.
Publicado: (2018)

Effects of Adenovirus-Mediated Overexpression of JAZF1 on Chronic Inflammation: An In Vitro and In Vivo Study
por: Meng, Fanping, et al.
Publicado: (2020)

Deletion of Jazf1 gene causes early growth retardation and insulin resistance in mice
por: Lee, Hui-Young, et al.
Publicado: (2022)

Identification of genetic variants associated with dengue or West Nile virus disease: a systematic review and meta-analysis
por: Cahill, Megan E., et al.
Publicado: (2018)

Novel genetic variants in long non-coding RNA MEG3 are associated with the risk of asthma
por: Chiu, Kuo-Liang, et al.
Publicado: (2023)

SEAGLE: A Scalable Exact Algorithm for Large-Scale Set-Based Gene-Environment Interaction Tests in Biobank Data
por: Chi, Jocelyn T., et al.
Publicado: (2021)

Fine Mapping of the MAP2K5 Region Identified rs7175517 as a Causal Variant Related to BMI in China and the United Kingdom Populations
por: Lu, Ce, et al.
Publicado: (2022)

The Public’s Awareness of and Attitude Toward Research Biobanks – A Regional German Survey
por: Bossert, Sabine, et al.
Publicado: (2018)

Using Image Recognition to Process Unbalanced Data in Genetic Diseases From Biobanks
por: Hsieh, Ai-Ru, et al.
Publicado: (2022)

Appropriate Safeguards and Article 89 of the GDPR: Considerations for Biobank, Databank and Genetic Research
por: Staunton, Ciara, et al.
Publicado: (2022)

The Informatics Challenges Facing Biobanks: A Perspective from a United Kingdom Biobanking Network
por: Quinlan, Philip R., et al.
Publicado: (2015)

A recurrent endometrial stromal sarcoma harbors the novel fusion JAZF1-BCORL1
por: Allen, Allison J, et al.
Publicado: (2017)

RNA-driven JAZF1-SUZ12 gene fusion in human endometrial stromal cells
por: Gupta, Sachin Kumar, et al.
Publicado: (2021)

Calculating Polygenic Risk Scores (PRS) in UK Biobank: A Practical Guide for Epidemiologists
por: Collister, Jennifer A., et al.
Publicado: (2022)

Race/ethnicity-stratified fine-mapping of the MHC locus reveals genetic variants associated with late-onset asthma
por: Lee, Eunice Y., et al.
Publicado: (2023)

Scalable and Robust Regression Methods for Phenome-Wide Association Analysis on Large-Scale Biobank Data
por: Bi, Wenjian, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_td2qcksh8tghc4vag0kb4vppsn