Synthesis of aliphatic nitriles from cyclobutanone oxime mediated by sulfuryl fluoride (SO(2)F(2))

A SO(2)F(2)-mediated ring-opening cross-coupling of cyclobutanone oxime derivatives with alkenes was developed for the construction of a range of δ-olefin-containing aliphatic nitriles with (E)-configuration selectivity. This new method features wide substrate scope, mild conditions, and direct N–O...

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Autores principales: Chen, Xian-Lin, Qin, Hua-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2023
Materias:
Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10291241/
https://www.ncbi.nlm.nih.gov/pubmed/37377774
http://dx.doi.org/10.3762/bjoc.19.68
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author Chen, Xian-Lin
Qin, Hua-Li
author_facet Chen, Xian-Lin
Qin, Hua-Li
author_sort Chen, Xian-Lin
collection PubMed
description A SO(2)F(2)-mediated ring-opening cross-coupling of cyclobutanone oxime derivatives with alkenes was developed for the construction of a range of δ-olefin-containing aliphatic nitriles with (E)-configuration selectivity. This new method features wide substrate scope, mild conditions, and direct N–O activation.
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spelling pubmed-102912412023-06-27 Synthesis of aliphatic nitriles from cyclobutanone oxime mediated by sulfuryl fluoride (SO(2)F(2)) Chen, Xian-Lin Qin, Hua-Li Beilstein J Org Chem Letter A SO(2)F(2)-mediated ring-opening cross-coupling of cyclobutanone oxime derivatives with alkenes was developed for the construction of a range of δ-olefin-containing aliphatic nitriles with (E)-configuration selectivity. This new method features wide substrate scope, mild conditions, and direct N–O activation. Beilstein-Institut 2023-06-22 /pmc/articles/PMC10291241/ /pubmed/37377774 http://dx.doi.org/10.3762/bjoc.19.68 Text en Copyright © 2023, Chen and Qin https://creativecommons.org/licenses/by/4.0/This is an open access article licensed under the terms of the Beilstein-Institut Open Access License Agreement (https://www.beilstein-journals.org/bjoc/terms/terms), which is identical to the Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0 (https://creativecommons.org/licenses/by/4.0/) ). The reuse of material under this license requires that the author(s), source and license are credited. Third-party material in this article could be subject to other licenses (typically indicated in the credit line), and in this case, users are required to obtain permission from the license holder to reuse the material.
spellingShingle Letter
Chen, Xian-Lin
Qin, Hua-Li
Synthesis of aliphatic nitriles from cyclobutanone oxime mediated by sulfuryl fluoride (SO(2)F(2))
title Synthesis of aliphatic nitriles from cyclobutanone oxime mediated by sulfuryl fluoride (SO(2)F(2))
title_full Synthesis of aliphatic nitriles from cyclobutanone oxime mediated by sulfuryl fluoride (SO(2)F(2))
title_fullStr Synthesis of aliphatic nitriles from cyclobutanone oxime mediated by sulfuryl fluoride (SO(2)F(2))
title_full_unstemmed Synthesis of aliphatic nitriles from cyclobutanone oxime mediated by sulfuryl fluoride (SO(2)F(2))
title_short Synthesis of aliphatic nitriles from cyclobutanone oxime mediated by sulfuryl fluoride (SO(2)F(2))
title_sort synthesis of aliphatic nitriles from cyclobutanone oxime mediated by sulfuryl fluoride (so(2)f(2))
topic Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10291241/
https://www.ncbi.nlm.nih.gov/pubmed/37377774
http://dx.doi.org/10.3762/bjoc.19.68
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