Quantum-based modeling implies that bidentate Arg(89)-substrate binding enhances serine/threonine protein phosphatase-2A(PPP2R5D/PPP2R1A/PPP2CA)-mediated dephosphorylation

PP2A-serine/threonine protein phosphatases function as heterotrimeric holoenzymes, composed of a common scaffold (A-subunit encoded by PPP2R1A/PPP2R1B), a common catalytic (C-subunit encoded by PPP2CA/PPP2CB), and one of many variable regulatory (B) subunits. The site of phosphoprotein phosphatase (...

Descripción completa

Detalles Bibliográficos
Autores principales: Salter, E. Alan, Wierzbicki, Andrzej, Honkanen, Richard E., Swingle, Mark R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10291244/
https://www.ncbi.nlm.nih.gov/pubmed/37377738
http://dx.doi.org/10.3389/fcell.2023.1141804

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10291244/
https://www.ncbi.nlm.nih.gov/pubmed/37377738
http://dx.doi.org/10.3389/fcell.2023.1141804

Ejemplares similares