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Time to clinical improvement: an appropriate surrogate endpoint for pulmonary arterial hypertension medication trials

BACKGROUND: Many retrospective studies suggest that risk improvement may be a suitable efficacy surrogate endpoint for pulmonary arterial hypertension (PAH) medication trials. This prospective multicenter study assessed the efficacy of domestic ambrisentan in Chinese PAH patients and observed risk i...

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Detalles Bibliográficos
Autores principales:	Wang, An, Chen, Mengqi, Zhuang, Qi, Guan, Lihua, Xie, Weiping, Wang, Lan, Huang, Wei, Cheng, Zhaozhong, Yu, Shiyong, Zhou, Hongmei, Shen, Jieyan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Cardiovascular Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10291317/ https://www.ncbi.nlm.nih.gov/pubmed/37378404 http://dx.doi.org/10.3389/fcvm.2023.1142721

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