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Attenuated Mycobacterium tuberculosis vaccine protection in a low-dose murine challenge model

Bacillus Calmette–Guérin (BCG) remains the only approved tuberculosis (TB) vaccine despite limited efficacy. Preclinical studies of next-generation TB vaccines typically use a murine aerosol model with a supraphysiologic challenge dose. Here, we show that the protective efficacy of a live attenuated...

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Detalles Bibliográficos
Autores principales:	Vidal, Samuel J., Sellers, Daniel, Yu, Jingyou, Wakabayashi, Shoko, Sixsmith, Jaimie, Aid, Malika, Barrett, Julia, Stevens, Sage F., Liu, Xiaowen, Li, Wenjun, Plumlee, Courtney R., Urdahl, Kevin B., Martinot, Amanda J., Barouch, Dan H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10291467/ https://www.ncbi.nlm.nih.gov/pubmed/37378347 http://dx.doi.org/10.1016/j.isci.2023.106963

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