Cargando…

A novel co-target of ACY1 governing plasma membrane translocation of SphK1 contributes to inflammatory and neuropathic pain

Previous studies validate that inhibiting sodium channel 1.8 (Nav1.8) effectively relieves inflammatory and neuropathic pain. However, Nav1.8 blockers have cardiac side effects in addition to analgesic effects. Here, we constructed a spinal differential protein expression profile using Nav1.8 knocko...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Baowen, Wu, Wenyao, Cui, LingLing, Zheng, Xuemei, Li, Ningbo, Zhang, Xianwei, Duan, Guangyou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10291574/
https://www.ncbi.nlm.nih.gov/pubmed/37378314
http://dx.doi.org/10.1016/j.isci.2023.106989