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IgYs: on her majesty’s secret service
There has been an increasing interest in using Immunoglobulin Y (IgY) antibodies as an alternative to “classical” antimicrobials. Unlike traditional antibiotics, they can be utilized on a continual basis without leading to the development of resistance. The veterinary IgY antibody market is growing...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10291628/ https://www.ncbi.nlm.nih.gov/pubmed/37377972 http://dx.doi.org/10.3389/fimmu.2023.1199427 |
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author | Grzywa, Renata Łupicka-Słowik, Agnieszka Sieńczyk, Marcin |
author_facet | Grzywa, Renata Łupicka-Słowik, Agnieszka Sieńczyk, Marcin |
author_sort | Grzywa, Renata |
collection | PubMed |
description | There has been an increasing interest in using Immunoglobulin Y (IgY) antibodies as an alternative to “classical” antimicrobials. Unlike traditional antibiotics, they can be utilized on a continual basis without leading to the development of resistance. The veterinary IgY antibody market is growing because of the demand for minimal antibiotic use in animal production. IgY antibodies are not as strong as antibiotics for treating infections, but they work well as preventative agents and are natural, nontoxic, and easy to produce. They can be administered orally and are well tolerated, even by young animals. Unlike antibiotics, oral IgY supplements support the microbiome that plays a vital role in maintaining overall health, including immune system function. IgY formulations can be delivered as egg yolk powder and do not require extensive purification. Lipids in IgY supplements improve antibody stability in the digestive tract. Given this, using IgY antibodies as an alternative to antimicrobials has garnered interest. In this review, we will examine their antibacterial potential. |
format | Online Article Text |
id | pubmed-10291628 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-102916282023-06-27 IgYs: on her majesty’s secret service Grzywa, Renata Łupicka-Słowik, Agnieszka Sieńczyk, Marcin Front Immunol Immunology There has been an increasing interest in using Immunoglobulin Y (IgY) antibodies as an alternative to “classical” antimicrobials. Unlike traditional antibiotics, they can be utilized on a continual basis without leading to the development of resistance. The veterinary IgY antibody market is growing because of the demand for minimal antibiotic use in animal production. IgY antibodies are not as strong as antibiotics for treating infections, but they work well as preventative agents and are natural, nontoxic, and easy to produce. They can be administered orally and are well tolerated, even by young animals. Unlike antibiotics, oral IgY supplements support the microbiome that plays a vital role in maintaining overall health, including immune system function. IgY formulations can be delivered as egg yolk powder and do not require extensive purification. Lipids in IgY supplements improve antibody stability in the digestive tract. Given this, using IgY antibodies as an alternative to antimicrobials has garnered interest. In this review, we will examine their antibacterial potential. Frontiers Media S.A. 2023-06-12 /pmc/articles/PMC10291628/ /pubmed/37377972 http://dx.doi.org/10.3389/fimmu.2023.1199427 Text en Copyright © 2023 Grzywa, Łupicka-Słowik and Sieńczyk https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Immunology Grzywa, Renata Łupicka-Słowik, Agnieszka Sieńczyk, Marcin IgYs: on her majesty’s secret service |
title | IgYs: on her majesty’s secret service |
title_full | IgYs: on her majesty’s secret service |
title_fullStr | IgYs: on her majesty’s secret service |
title_full_unstemmed | IgYs: on her majesty’s secret service |
title_short | IgYs: on her majesty’s secret service |
title_sort | igys: on her majesty’s secret service |
topic | Immunology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10291628/ https://www.ncbi.nlm.nih.gov/pubmed/37377972 http://dx.doi.org/10.3389/fimmu.2023.1199427 |
work_keys_str_mv | AT grzywarenata igysonhermajestyssecretservice AT łupickasłowikagnieszka igysonhermajestyssecretservice AT sienczykmarcin igysonhermajestyssecretservice |