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IgYs: on her majesty’s secret service

There has been an increasing interest in using Immunoglobulin Y (IgY) antibodies as an alternative to “classical” antimicrobials. Unlike traditional antibiotics, they can be utilized on a continual basis without leading to the development of resistance. The veterinary IgY antibody market is growing...

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Autores principales: Grzywa, Renata, Łupicka-Słowik, Agnieszka, Sieńczyk, Marcin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10291628/
https://www.ncbi.nlm.nih.gov/pubmed/37377972
http://dx.doi.org/10.3389/fimmu.2023.1199427
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author Grzywa, Renata
Łupicka-Słowik, Agnieszka
Sieńczyk, Marcin
author_facet Grzywa, Renata
Łupicka-Słowik, Agnieszka
Sieńczyk, Marcin
author_sort Grzywa, Renata
collection PubMed
description There has been an increasing interest in using Immunoglobulin Y (IgY) antibodies as an alternative to “classical” antimicrobials. Unlike traditional antibiotics, they can be utilized on a continual basis without leading to the development of resistance. The veterinary IgY antibody market is growing because of the demand for minimal antibiotic use in animal production. IgY antibodies are not as strong as antibiotics for treating infections, but they work well as preventative agents and are natural, nontoxic, and easy to produce. They can be administered orally and are well tolerated, even by young animals. Unlike antibiotics, oral IgY supplements support the microbiome that plays a vital role in maintaining overall health, including immune system function. IgY formulations can be delivered as egg yolk powder and do not require extensive purification. Lipids in IgY supplements improve antibody stability in the digestive tract. Given this, using IgY antibodies as an alternative to antimicrobials has garnered interest. In this review, we will examine their antibacterial potential.
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spelling pubmed-102916282023-06-27 IgYs: on her majesty’s secret service Grzywa, Renata Łupicka-Słowik, Agnieszka Sieńczyk, Marcin Front Immunol Immunology There has been an increasing interest in using Immunoglobulin Y (IgY) antibodies as an alternative to “classical” antimicrobials. Unlike traditional antibiotics, they can be utilized on a continual basis without leading to the development of resistance. The veterinary IgY antibody market is growing because of the demand for minimal antibiotic use in animal production. IgY antibodies are not as strong as antibiotics for treating infections, but they work well as preventative agents and are natural, nontoxic, and easy to produce. They can be administered orally and are well tolerated, even by young animals. Unlike antibiotics, oral IgY supplements support the microbiome that plays a vital role in maintaining overall health, including immune system function. IgY formulations can be delivered as egg yolk powder and do not require extensive purification. Lipids in IgY supplements improve antibody stability in the digestive tract. Given this, using IgY antibodies as an alternative to antimicrobials has garnered interest. In this review, we will examine their antibacterial potential. Frontiers Media S.A. 2023-06-12 /pmc/articles/PMC10291628/ /pubmed/37377972 http://dx.doi.org/10.3389/fimmu.2023.1199427 Text en Copyright © 2023 Grzywa, Łupicka-Słowik and Sieńczyk https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Immunology
Grzywa, Renata
Łupicka-Słowik, Agnieszka
Sieńczyk, Marcin
IgYs: on her majesty’s secret service
title IgYs: on her majesty’s secret service
title_full IgYs: on her majesty’s secret service
title_fullStr IgYs: on her majesty’s secret service
title_full_unstemmed IgYs: on her majesty’s secret service
title_short IgYs: on her majesty’s secret service
title_sort igys: on her majesty’s secret service
topic Immunology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10291628/
https://www.ncbi.nlm.nih.gov/pubmed/37377972
http://dx.doi.org/10.3389/fimmu.2023.1199427
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