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Transcriptome- and proteome-wide association studies nominate determinants of kidney function and damage
BACKGROUND: The pathophysiological causes of kidney disease are not fully understood. Here we show that the integration of genome-wide genetic, transcriptomic, and proteomic association studies can nominate causal determinants of kidney function and damage. RESULTS: Through transcriptome-wide associ...
Autores principales: | Schlosser, Pascal, Zhang, Jingning, Liu, Hongbo, Surapaneni, Aditya L., Rhee, Eugene P., Arking, Dan E., Yu, Bing, Boerwinkle, Eric, Welling, Paul A., Chatterjee, Nilanjan, Susztak, Katalin, Coresh, Josef, Grams, Morgan E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10291807/ https://www.ncbi.nlm.nih.gov/pubmed/37365616 http://dx.doi.org/10.1186/s13059-023-02993-y |
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