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Regulatory mechanisms and therapeutic potential of JAB1 in neurological development and disorders

c-Jun activation domain binding protein-1 (JAB1) is a multifunctional regulator that plays vital roles in diverse cellular processes. It regulates AP-1 transcriptional activity and also acts as the fifth component of the COP9 signalosome complex. While JAB1 is considered an oncoprotein that triggers...

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Detalles Bibliográficos
Autores principales: Yang, Yu, Song, Ruying, Gao, Yiming, Yu, Hao, Wang, Shuai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10291812/
https://www.ncbi.nlm.nih.gov/pubmed/37365502
http://dx.doi.org/10.1186/s10020-023-00675-w