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Pediatric Posterior Reversible Encephalopathy Syndrome Secondary to Post-Streptococcal Glomerulonephritis: A Case Report

This case report presents a unique case of a 15-year-old male with post-streptococcal glomerulonephritis (PSGN) who developed posterior reversible encephalopathy syndrome (PRES). The patient presented with symptoms of fever, headache, emesis, visual disturbances, and involuntary movements of all fou...

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Autores principales: Harikrishna, Ganaraja V, CA, Jayashankar, Joshi, Amey, Shuhab, Aman, Kodapala, Suresha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10292161/
https://www.ncbi.nlm.nih.gov/pubmed/37378234
http://dx.doi.org/10.7759/cureus.38996
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author Harikrishna, Ganaraja V
CA, Jayashankar
Joshi, Amey
Shuhab, Aman
Kodapala, Suresha
author_facet Harikrishna, Ganaraja V
CA, Jayashankar
Joshi, Amey
Shuhab, Aman
Kodapala, Suresha
author_sort Harikrishna, Ganaraja V
collection PubMed
description This case report presents a unique case of a 15-year-old male with post-streptococcal glomerulonephritis (PSGN) who developed posterior reversible encephalopathy syndrome (PRES). The patient presented with symptoms of fever, headache, emesis, visual disturbances, and involuntary movements of all four limbs. On examination, the patient had elevated blood pressure, decreased visual acuity of the left eye, leukocytosis, and uremia. MRI findings showed symmetrical enhancement of superficial and deep watershed areas, predominantly in the occipital and temporal regions. Treatment with antibiotics and anti-hypertensives resulted in the complete resolution of hyperintense lesions seen in brain MRI after three weeks, and the patient remained symptom-free for one month. This case highlights the rare association between PSGN and PRES and emphasizes the importance of monitoring and managing hypertension in patients with PSGN. Understanding the association between these two conditions may lead to earlier diagnosis and treatment of PRES, ultimately improving patient outcomes.
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spelling pubmed-102921612023-06-27 Pediatric Posterior Reversible Encephalopathy Syndrome Secondary to Post-Streptococcal Glomerulonephritis: A Case Report Harikrishna, Ganaraja V CA, Jayashankar Joshi, Amey Shuhab, Aman Kodapala, Suresha Cureus Neurology This case report presents a unique case of a 15-year-old male with post-streptococcal glomerulonephritis (PSGN) who developed posterior reversible encephalopathy syndrome (PRES). The patient presented with symptoms of fever, headache, emesis, visual disturbances, and involuntary movements of all four limbs. On examination, the patient had elevated blood pressure, decreased visual acuity of the left eye, leukocytosis, and uremia. MRI findings showed symmetrical enhancement of superficial and deep watershed areas, predominantly in the occipital and temporal regions. Treatment with antibiotics and anti-hypertensives resulted in the complete resolution of hyperintense lesions seen in brain MRI after three weeks, and the patient remained symptom-free for one month. This case highlights the rare association between PSGN and PRES and emphasizes the importance of monitoring and managing hypertension in patients with PSGN. Understanding the association between these two conditions may lead to earlier diagnosis and treatment of PRES, ultimately improving patient outcomes. Cureus 2023-05-14 /pmc/articles/PMC10292161/ /pubmed/37378234 http://dx.doi.org/10.7759/cureus.38996 Text en Copyright © 2023, Harikrishna et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Neurology
Harikrishna, Ganaraja V
CA, Jayashankar
Joshi, Amey
Shuhab, Aman
Kodapala, Suresha
Pediatric Posterior Reversible Encephalopathy Syndrome Secondary to Post-Streptococcal Glomerulonephritis: A Case Report
title Pediatric Posterior Reversible Encephalopathy Syndrome Secondary to Post-Streptococcal Glomerulonephritis: A Case Report
title_full Pediatric Posterior Reversible Encephalopathy Syndrome Secondary to Post-Streptococcal Glomerulonephritis: A Case Report
title_fullStr Pediatric Posterior Reversible Encephalopathy Syndrome Secondary to Post-Streptococcal Glomerulonephritis: A Case Report
title_full_unstemmed Pediatric Posterior Reversible Encephalopathy Syndrome Secondary to Post-Streptococcal Glomerulonephritis: A Case Report
title_short Pediatric Posterior Reversible Encephalopathy Syndrome Secondary to Post-Streptococcal Glomerulonephritis: A Case Report
title_sort pediatric posterior reversible encephalopathy syndrome secondary to post-streptococcal glomerulonephritis: a case report
topic Neurology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10292161/
https://www.ncbi.nlm.nih.gov/pubmed/37378234
http://dx.doi.org/10.7759/cureus.38996
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