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Successful Management of Rhino-Orbital-Cerebral Mucormycosis in a Child with Acute-on-Chronic Kidney Disease and Malnutrition: Case report and literature review
Mucormycosis is a very rare fungal infection in children. It is caused by opportunistic fungi and mainly affects immunocompromised patients. Early diagnosis is very important for a good outcome. Successful management requires the reversal of the underlying predisposing risk factors, surgical debride...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Sultan Qaboos University Medical Journal, College of Medicine & Health Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10292589/ https://www.ncbi.nlm.nih.gov/pubmed/37377827 http://dx.doi.org/10.18295/squmj.3.2022.025 |
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author | Al Reesi, Mohammed Al Muqbali, Taleb Al Ajmi, Ahmed Menon, Varna |
author_facet | Al Reesi, Mohammed Al Muqbali, Taleb Al Ajmi, Ahmed Menon, Varna |
author_sort | Al Reesi, Mohammed |
collection | PubMed |
description | Mucormycosis is a very rare fungal infection in children. It is caused by opportunistic fungi and mainly affects immunocompromised patients. Early diagnosis is very important for a good outcome. Successful management requires the reversal of the underlying predisposing risk factors, surgical debridement and prompt administration of active antifungal agents, with liposomal amphotericin B being the first-line therapy. This case, to the best of the authors’ knowledge, is the first rhino-orbital-cerebral mucormycosis to be reported on among Omani children. We highlight the importance of early diagnosis and prompt surgical and medical interventions in achieving a satisfactory outcome and review the published literature in regard to the management. |
format | Online Article Text |
id | pubmed-10292589 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Sultan Qaboos University Medical Journal, College of Medicine & Health Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-102925892023-06-27 Successful Management of Rhino-Orbital-Cerebral Mucormycosis in a Child with Acute-on-Chronic Kidney Disease and Malnutrition: Case report and literature review Al Reesi, Mohammed Al Muqbali, Taleb Al Ajmi, Ahmed Menon, Varna Sultan Qaboos Univ Med J Case Report Mucormycosis is a very rare fungal infection in children. It is caused by opportunistic fungi and mainly affects immunocompromised patients. Early diagnosis is very important for a good outcome. Successful management requires the reversal of the underlying predisposing risk factors, surgical debridement and prompt administration of active antifungal agents, with liposomal amphotericin B being the first-line therapy. This case, to the best of the authors’ knowledge, is the first rhino-orbital-cerebral mucormycosis to be reported on among Omani children. We highlight the importance of early diagnosis and prompt surgical and medical interventions in achieving a satisfactory outcome and review the published literature in regard to the management. Sultan Qaboos University Medical Journal, College of Medicine & Health Sciences 2023-05 2023-05-31 /pmc/articles/PMC10292589/ /pubmed/37377827 http://dx.doi.org/10.18295/squmj.3.2022.025 Text en © Copyright 2023, Sultan Qaboos University Medical Journal, All Rights Reserved https://creativecommons.org/licenses/by-nd/4.0/This work is licensed under a Creative Commons Attribution-NoDerivatives 4.0 International License. |
spellingShingle | Case Report Al Reesi, Mohammed Al Muqbali, Taleb Al Ajmi, Ahmed Menon, Varna Successful Management of Rhino-Orbital-Cerebral Mucormycosis in a Child with Acute-on-Chronic Kidney Disease and Malnutrition: Case report and literature review |
title | Successful Management of Rhino-Orbital-Cerebral Mucormycosis in a Child with Acute-on-Chronic Kidney Disease and Malnutrition: Case report and literature review |
title_full | Successful Management of Rhino-Orbital-Cerebral Mucormycosis in a Child with Acute-on-Chronic Kidney Disease and Malnutrition: Case report and literature review |
title_fullStr | Successful Management of Rhino-Orbital-Cerebral Mucormycosis in a Child with Acute-on-Chronic Kidney Disease and Malnutrition: Case report and literature review |
title_full_unstemmed | Successful Management of Rhino-Orbital-Cerebral Mucormycosis in a Child with Acute-on-Chronic Kidney Disease and Malnutrition: Case report and literature review |
title_short | Successful Management of Rhino-Orbital-Cerebral Mucormycosis in a Child with Acute-on-Chronic Kidney Disease and Malnutrition: Case report and literature review |
title_sort | successful management of rhino-orbital-cerebral mucormycosis in a child with acute-on-chronic kidney disease and malnutrition: case report and literature review |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10292589/ https://www.ncbi.nlm.nih.gov/pubmed/37377827 http://dx.doi.org/10.18295/squmj.3.2022.025 |
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