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Successful Management of Rhino-Orbital-Cerebral Mucormycosis in a Child with Acute-on-Chronic Kidney Disease and Malnutrition: Case report and literature review

Mucormycosis is a very rare fungal infection in children. It is caused by opportunistic fungi and mainly affects immunocompromised patients. Early diagnosis is very important for a good outcome. Successful management requires the reversal of the underlying predisposing risk factors, surgical debride...

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Autores principales: Al Reesi, Mohammed, Al Muqbali, Taleb, Al Ajmi, Ahmed, Menon, Varna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sultan Qaboos University Medical Journal, College of Medicine & Health Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10292589/
https://www.ncbi.nlm.nih.gov/pubmed/37377827
http://dx.doi.org/10.18295/squmj.3.2022.025
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author Al Reesi, Mohammed
Al Muqbali, Taleb
Al Ajmi, Ahmed
Menon, Varna
author_facet Al Reesi, Mohammed
Al Muqbali, Taleb
Al Ajmi, Ahmed
Menon, Varna
author_sort Al Reesi, Mohammed
collection PubMed
description Mucormycosis is a very rare fungal infection in children. It is caused by opportunistic fungi and mainly affects immunocompromised patients. Early diagnosis is very important for a good outcome. Successful management requires the reversal of the underlying predisposing risk factors, surgical debridement and prompt administration of active antifungal agents, with liposomal amphotericin B being the first-line therapy. This case, to the best of the authors’ knowledge, is the first rhino-orbital-cerebral mucormycosis to be reported on among Omani children. We highlight the importance of early diagnosis and prompt surgical and medical interventions in achieving a satisfactory outcome and review the published literature in regard to the management.
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spelling pubmed-102925892023-06-27 Successful Management of Rhino-Orbital-Cerebral Mucormycosis in a Child with Acute-on-Chronic Kidney Disease and Malnutrition: Case report and literature review Al Reesi, Mohammed Al Muqbali, Taleb Al Ajmi, Ahmed Menon, Varna Sultan Qaboos Univ Med J Case Report Mucormycosis is a very rare fungal infection in children. It is caused by opportunistic fungi and mainly affects immunocompromised patients. Early diagnosis is very important for a good outcome. Successful management requires the reversal of the underlying predisposing risk factors, surgical debridement and prompt administration of active antifungal agents, with liposomal amphotericin B being the first-line therapy. This case, to the best of the authors’ knowledge, is the first rhino-orbital-cerebral mucormycosis to be reported on among Omani children. We highlight the importance of early diagnosis and prompt surgical and medical interventions in achieving a satisfactory outcome and review the published literature in regard to the management. Sultan Qaboos University Medical Journal, College of Medicine & Health Sciences 2023-05 2023-05-31 /pmc/articles/PMC10292589/ /pubmed/37377827 http://dx.doi.org/10.18295/squmj.3.2022.025 Text en © Copyright 2023, Sultan Qaboos University Medical Journal, All Rights Reserved https://creativecommons.org/licenses/by-nd/4.0/This work is licensed under a Creative Commons Attribution-NoDerivatives 4.0 International License.
spellingShingle Case Report
Al Reesi, Mohammed
Al Muqbali, Taleb
Al Ajmi, Ahmed
Menon, Varna
Successful Management of Rhino-Orbital-Cerebral Mucormycosis in a Child with Acute-on-Chronic Kidney Disease and Malnutrition: Case report and literature review
title Successful Management of Rhino-Orbital-Cerebral Mucormycosis in a Child with Acute-on-Chronic Kidney Disease and Malnutrition: Case report and literature review
title_full Successful Management of Rhino-Orbital-Cerebral Mucormycosis in a Child with Acute-on-Chronic Kidney Disease and Malnutrition: Case report and literature review
title_fullStr Successful Management of Rhino-Orbital-Cerebral Mucormycosis in a Child with Acute-on-Chronic Kidney Disease and Malnutrition: Case report and literature review
title_full_unstemmed Successful Management of Rhino-Orbital-Cerebral Mucormycosis in a Child with Acute-on-Chronic Kidney Disease and Malnutrition: Case report and literature review
title_short Successful Management of Rhino-Orbital-Cerebral Mucormycosis in a Child with Acute-on-Chronic Kidney Disease and Malnutrition: Case report and literature review
title_sort successful management of rhino-orbital-cerebral mucormycosis in a child with acute-on-chronic kidney disease and malnutrition: case report and literature review
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10292589/
https://www.ncbi.nlm.nih.gov/pubmed/37377827
http://dx.doi.org/10.18295/squmj.3.2022.025
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