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Cat LCA-CRX Model, Homozygous for an Antimorphic Mutation Has a Unique Phenotype
PURPOSE: Mutations in the CRX transcription factor are associated with dominant retinopathies often with more severe macular changes. The CRX-mutant cat (Rdy-A182d2) is the only animal model with the equivalent of the critical retinal region for high-acuity vision, the macula. Heterozygous cats (CRX...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Association for Research in Vision and Ophthalmology
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10292669/ https://www.ncbi.nlm.nih.gov/pubmed/37351895 http://dx.doi.org/10.1167/tvst.12.6.15 |